Reproduction in the bacterial kingdom predominantly occurs through binary fission—a
process in which one parental cell is divided into two similarly sized daughter cells. How cell …

The FtsEX complex regulates, directly or via a protein mediator depending on bacterial
genera, peptidoglycan degradation for cell division. In mycobacteria and Gram-positive …

How do mycobacteria divide? Cell division has been studied extensively in the model rod-
shaped bacteria Escherichia coli and Bacillus subtilis, but much less is understood about …

The success of Mycobacterium tuberculosis (Mtb) is largely attributed to its ability to
physiologically adapt and withstand diverse localized stresses within host …

Mycobacterium tuberculosis possesses a large number of genes of unknown or predicted
function, undermining fundamental understanding of pathogenicity and drug susceptibility …

Mycobacterium abscessus (Mab) is a rapidly growing non-tuberculous mycobacterium
(NTM) that causes a wide range of infections. Treatment of Mab infections is difficult because …

Functional characterization of bacterial proteins lags far behind the identification of new
protein families. This is especially true for bacterial species that are more difficult to grow …

Mtb infects a quarter of the worldwide population. Most drugs for treating tuberculosis target
cell growth and division. With rising drug resistance, it becomes ever more urgent to better …

Although prokaryotic organisms lack traditional organelles, they must still organize cellular
structures in space and time, challenges that different species solve differently. To …

The bacterial cell wall is a multi-layered mesh, whose major component is peptidoglycan
(PG), a sugar polymer cross-linked by short peptide stems. During cell division, a careful …