Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and
filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized …

Streptococcus pneumoniae (the pneumococcus) is a common colonizer of the human
nasopharynx. Despite a low rate of invasive disease, the high prevalence of colonization …

The interest in nanotechnology and the growing concern for the antibiotic resistance
demonstrated by many microorganisms have recently stimulated many efforts in designing …

Background The vaginal microbiota can impact the susceptibility of women to bacterial
vaginosis (BV) and sexually transmitted infections (STIs). BV is characterized by depletion of …

Otitis media is a common childhood infection of the middle ear and a major cause of
morbidity. This multifactorial disease manifests as a spectrum of clinical syndromes from …

It has long been thought that respiratory infections are the direct result of acquisition of
pathogenic viruses or bacteria, followed by their overgrowth, dissemination, and in some …

Streptococcus pneumoniae is a leading cause of infectious disease globally.
Nasopharyngeal colonization occurs in biofilms and precedes infection. Prior studies have …

Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an
opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage …

Streptococcus pneumoniae is an opportunistic pathogen that causes over 1 million deaths
annually despite the availability of several multivalent pneumococcal conjugate vaccines …