Toward automated oligosaccharide synthesis

CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

Glycan arrays: recent advances and future challenges

O Oyelaran, JC Gildersleeve - Current opinion in chemical biology, 2009 - Elsevier
Carbohydrate arrays, also referred to as glycan arrays, are composed of various
oligosaccharides and/or polysaccharides immobilized on a solid support in a spatially …

Microbial glycan microarrays define key features of host-microbial interactions

SR Stowell, CM Arthur, R McBride, O Berger… - Nature chemical …, 2014 - nature.com
Genomic approaches continue to provide unprecedented insight into the microbiome, yet
host immune interactions with diverse microbiota can be difficult to study. We therefore …

Microbe-focused glycan array screening platform

A Geissner, A Reinhardt… - Proceedings of the …, 2019 - National Acad Sciences
Interactions between glycans and glycan binding proteins are essential for numerous
processes in all kingdoms of life. Glycan microarrays are an excellent tool to examine …

Profiling human serum antibodies with a carbohydrate antigen microarray

O Oyelaran, LM McShane, L Dodd… - Journal of proteome …, 2009 - ACS Publications
Carbohydrate antigen arrays (glycan arrays) have been recently developed for the high-
throughput analysis of carbohydrate macromolecule interactions. When profiling serum …

Glycan and lectin microarrays for glycomics and medicinal applications

J Katrlík, J Švitel, P Gemeiner, T Kožár… - Medicinal research …, 2010 - Wiley Online Library
Three different array formats to study a challenging field of glycomics are presented here,
based on the use of a panel of immobilized glycan or lectins, and on in silico computational …

Factors affecting anti-glycan IgG and IgM repertoires in human serum

SM Muthana, JC Gildersleeve - Scientific reports, 2016 - nature.com
Serum anti-glycan antibodies play important roles in many immune processes and are of
particular interest as biomarkers for many diseases. Changes in anti-glycan antibodies can …

Serum antibody screening using glycan arrays

S Marglous, CE Brown, V Padler-Karavani… - Chemical Society …, 2024 - pubs.rsc.org
Humans and other animals produce a diverse collection of antibodies, many of which bind to
carbohydrate chains, referred to as glycans. These anti-glycan antibodies are a critical part …

Glycan microarrays: powerful tools for biomarker discovery

SM Muthana, JC Gildersleeve - Cancer Biomarkers, 2014 - content.iospress.com
Over the last 10 years, glycan microarray technology has emerged as a powerful high-
throughput tool for studying the interactions of carbohydrates with a variety of biomolecules …

[HTML][HTML] Evaluation of polysaccharide-based latex agglutination assays for the rapid detection of antibodies to Burkholderia pseudomallei

V Suttisunhakul, N Chantratita… - The American journal …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease caused by the Gram-negative bacterium Burkholderia
pseudomallei. Diagnosis of melioidosis currently relies on the isolation of B. pseudomallei …