Neuroinflammation has become a key hallmark of neurological complications including
perioperative pathologies such as postoperative delirium and longer-lasting postoperative …

Trauma experienced during surgery can contribute to the development of a systemic
inflammatory response that can cause multi-organ dysfunction or even failure. Post-surgical …

Sevoflurane is one of the most widely used anesthetics for the induction and maintenance of
general anesthesia in surgical patients. Sevoflurane treatment may increase the incidence …

Background Surgery-induced neuroinflammation plays an important role in postoperative
cognitive dysfunction (POCD). Gut microbiota is a key regulator of neurological …

Postoperative cognitive dysfunction (POCD) is a debilitating surgical complication, with
cardiac surgery patients at particular risk. To gain insight in the mechanisms underlying the …

Background Elderly patients often exhibit postoperative cognitive dysfunction (POCD), a
postsurgical decline in memory and executive function. Oxidative stress and …

Postoperative neurocognitive disorder (PND) increases the length of hospital stay, mortality,
and risk of long-term cognitive impairment. Perioperative sleep disturbance is prevalent and …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that targets memory
and cognition, and is the most common form of dementia among the elderly. Although AD …

Pain is a critical component hindering recovery and regaining of function after surgery,
particularly in the elderly. Understanding the role of pain signaling after surgery may lead to …

Aims Postoperative cognitive dysfunction (POCD) is a common and significant syndrome.
Our previous studies have shown that surgery reduces dendritic arborization and spine …