Bioinformatics approaches to discovering food-derived bioactive peptides: Reviews and perspectives

Z Du, J Comer, Y Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Food-derived bioactive peptides (FBPs) are gaining interest due to their great potential in
agricultural byproduct valorization and high-activity peptide screening. The introduction of …

[HTML][HTML] Immunomodulatory peptides—A promising source for novel functional food production and drug discovery

M Pavlicevic, N Marmiroli, E Maestri - Peptides, 2022 - Elsevier
Immunomodulatory peptides are a complex class of bioactive peptides that encompasses
substances with different mechanisms of action. Immunomodulatory peptides could also be …

Identification and molecular mechanism of novel immunomodulatory peptides from gelatin hydrolysates: Molecular docking, dynamic simulation, and cell experiments

Z Yu, Y Wang, D Shuian, J Liu… - Journal of Agricultural and …, 2023 - ACS Publications
The purpose of this study was to identify donkey-hide gelatin-derived immunomodulatory
peptides targeting Toll-like receptor 4-myeloid differentiation 2 (TLR4-MD2) and elucidate …

Plant protein-based delivery systems: An emerging approach for increasing the efficacy of lipophilic bioactive compounds

A Gomes, PJA Sobral - Molecules, 2021 - mdpi.com
The development of plant protein-based delivery systems to protect and control lipophilic
bioactive compound delivery (such as vitamins, polyphenols, carotenoids, polyunsaturated …

Glycosylation of rice protein with dextran via the Maillard reaction in a macromolecular crowding condition to improve solubility

YH Cheng, DC Mu, YY Feng, Z Xu, L Wen… - Journal of Cereal …, 2022 - Elsevier
The study aims at improving the solubility of rice protein (RP) by covalent coupling of
proteins to polysaccharide via Maillard reaction in macromolecular crowding conditions. The …

Identification and in silico analysis of novel antioxidant peptides in broken rice protein hydrolysate and its cytoprotective effect against H2O2-induced 2BS cell model

L Ren, Y Yang, C Ma, J Fan, X Bian, B Liu… - Food Research …, 2022 - Elsevier
Broken rice is an important by-product during milling process of rice, which is rich in protein.
To increase the value of by-products and search for effective antioxidants, the antioxidant …

Anti-inflammatory effect of two novel peptides derived from Binglangjiang buffalo whey protein in lipopolysaccharide-stimulated RAW264. 7 macrophages

Q Zhao, W Zheng, Z Yuan, X Wang, A Huang - Food Chemistry, 2023 - Elsevier
Whey protein hydrolysate from Binglangjiang buffalo, a unique genetic resource, has anti-
inflammatory activity, but its anti-inflammatory composition and effects are unknown. The aim …

Rapid Screening of Novel Dipeptidyl Peptidase-4 Inhibitory Peptides from Pea (Pisum sativum L.) Protein Using Peptidomics and Molecular Docking

M Zhang, L Zhu, G Wu, T Liu, X Qi… - Journal of Agricultural …, 2022 - ACS Publications
Pea protein hydrolysates (PPHs) possess good hypoglycemic effects; however, their
dipeptidyl peptidase-4 (DPP-4) inhibitory activity is poorly understood, and none of the DPP …

Plant Protein-Derived Active Peptides: A Comprehensive Review

F Zhu, J Cao, Y Song, P Yu, E Su - Journal of Agricultural and …, 2023 - ACS Publications
Active peptides are a class of physiologically active protein fragments, which can be
prepared from different sources. In the past few decades, the production of peptides with …

Industrially produced rice protein ameliorates dextran sulfate sodium-induced colitis via protecting the intestinal barrier, mitigating oxidative stress, and regulating gut …

Z Huang, W Yang, X Wang, F Guo… - Journal of Agricultural …, 2022 - ACS Publications
Inflammatory bowel disease (IBD) poses a threat to health and compromises the immune
system and gut microflora. The present study aimed to explore the effects of rice protein (RP) …