N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease

D Olivares, VK Deshpande, Y Shi… - Current Alzheimer …, 2012 - ingentaconnect.com
Memantine, a partial antagonist of N-methyl-D-aspartate receptor (NMDAR), approved for
moderate to severe Alzheimer's disease (AD) treatment within the US and Europe under …

Natural rewards, neuroplasticity, and non-drug addictions

CM Olsen - Neuropharmacology, 2011 - Elsevier
There is a high degree of overlap between brain regions involved in processing natural
rewards and drugs of abuse.“Non-drug” or “behavioral” addictions have become …

Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation

SB Raut, PA Marathe, L van Eijk, R Eri… - Pharmacology & …, 2022 - Elsevier
Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Stress, neurotransmitters, corticosterone and body–brain integration

F Mora, G Segovia, A Del Arco, M de Blas, P Garrido - Brain research, 2012 - Elsevier
Stress can be defined as a brain–body reaction towards stimuli arising from the environment
or from internal cues that are interpreted as a disruption of homeostasis. The organization of …

A preliminary choroid plexus volumetric study in individuals with psychosis

O Senay, M Seethaler, N Makris… - Human Brain …, 2023 - Wiley Online Library
The choroid plexus (ChP) is part of the blood‐cerebrospinal fluid barrier, regulating brain
homeostasis and the brain's response to peripheral events. Its upregulation and …

PTSD: from neurobiology to pharmacological treatments

B Kelmendi, TG Adams, S Yarnell… - European journal of …, 2016 - Taylor & Francis
Posttraumatic stress disorder (PTSD) is a chronic debilitating psychiatric disorder
characterized by symptoms of re-experience, avoidance, and hyperarousal that can arise …

Current intensity‐and polarity‐specific online and aftereffects of transcranial direct current stimulation: An fMRI study

A Jamil, G Batsikadze, HI Kuo, RLJ Meesen… - Human brain …, 2020 - Wiley Online Library
Transcranial direct current stimulation (tDCS) induces polarity‐and dose‐dependent
neuroplastic aftereffects on cortical excitability and cortical activity, as demonstrated by …

Brain glutamate levels measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta‐analysis

AD Gigante, DJ Bond, B Lafer, RW Lam… - Bipolar …, 2012 - Wiley Online Library
Gigante AD, Bond DJ, Lafer B, Lam RW, Young LT, Yatham LN. Brain glutamate levels
measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta …

Pharmacological treatment of PTSD–established and new approaches

T Steckler, V Risbrough - Neuropharmacology, 2012 - Elsevier
A large proportion of humans will experience a traumatic event at least once in their lifetime,
with up to 10% then going on to developing posttraumatic stress disorder (PTSD). In this …

Molecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disorders

D Schubert, GJM Martens, SM Kolk - Molecular psychiatry, 2015 - nature.com
The prefrontal cortex (PFC), seat of the highest-order cognitive functions, constitutes a
conglomerate of highly specialized brain areas and has been implicated to have a role in …