Influence of body weight on bone mass, architecture and turnover

UT Iwaniec, RT Turner - Journal of Endocrinology, 2016 - joe.bioscientifica.com
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus
increasing blood volume and pressure. Excessive production of aldosterone results in high …

Obesity and fractures

MO Premaor, FV Comim, JE Compston - Arquivos Brasileiros de …, 2014 - SciELO Brasil
Until recently obesity was believed to be protective against fractures. However, a report from
a Fracture Liaison Clinic in the UK (2010) reported a surprisingly high proportion of obese …

“Obesity paradox” holds true for patients with hip fracture: a registry-based cohort study

K Modig, A Erdefelt, C Mellner, T Cederholm… - JBJS, 2019 - journals.lww.com
Background: Hip fractures are associated with high mortality and reduced quality of life.
Studies have reported a high body mass index (BMI) as being positively associated with …

Incident type 2 diabetes and hip fracture risk: a population-based matched cohort study

D Martinez-Laguna, C Tebe, MK Javaid… - Osteoporosis …, 2015 - Springer
There is scarce data on the association between early stages of type 2 diabetes and fracture
risk. We report a 20% excess risk of hip fracture in the first years following disease onset …

Effect of sarcopenia on clinical and surgical outcome in elderly patients with proximal femur fractures

CD Chang, JS Wu, JN Mhuircheartaigh, MG Hochman… - Skeletal radiology, 2018 - Springer
Purpose To investigate the relationship between sarcopenia with short-term surgical
outcome in elderly patients with proximal femur fractures. Methods and materials Following …

Insulin use and excess fracture risk in patients with type 2 diabetes: a propensity-matched cohort analysis

E Losada-Grande, S Hawley, B Soldevila… - Scientific Reports, 2017 - nature.com
Despite normal to high bone mineral density, patients with type 2 diabetes (T2DM) have an
increased fracture risk. T2DM medications could partially account for this excess risk. The …

Comorbidities only account for a small proportion of excess mortality after fracture: a record linkage study of individual fracture types

W Chen, JM Simpson, LM March… - Journal of Bone and …, 2018 - academic.oup.com
Nonhip, nonvertebral (NHNV) fractures constitute the majority of osteoporotic fractures, but
few studies have examined the association between these fractures, comorbidity, and …

[HTML][HTML] Analyzing the risk factors of mortality after osteoporotic hip fractures using the national health insurance service sample cohort 2.0 database

HJ Chung, DS Kim, JW Lee, SI Hong - Hip & pelvis, 2022 - ncbi.nlm.nih.gov
Purpose The purpose of this study is to determine risk factors that affect mortality following
osteoporotic hip fracture in patients 50 years or older using the National Health Insurance …

Obesity paradox, obesity orthodox, and the metabolic syndrome: an approach to unity

J Roth, N Sahota, P Patel, SF Mehdi, MM Wiese… - Molecular …, 2016 - Springer
Obesity and its accompanying metabolic syndrome are strongly associated with heightened
morbidity and mortality in older adults. In our review of more than 20 epidemiologic studies …

Body mass index and all-cause mortality in chronic kidney disease: a dose–response meta-analysis of observational studies

M Rahimlu, S Shab-Bidar, K Djafarian - Journal of Renal Nutrition, 2017 - Elsevier
This article provides a dose–response meta-analysis to evaluate the relationship between
body mass index (BMI) and all-cause and disease-specific mortality in chronic kidney …