Exploring vitamin D metabolism and function in cancer

SM Jeon, EA Shin - Experimental & molecular medicine, 2018 - nature.com
Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid
hormone that regulates a broad spectrum of physiological processes. In addition to its …

Hyperparathyroidism

JP Bilezikian, L Bandeira, A Khan, NE Cusano - The Lancet, 2018 - thelancet.com
Primary hyperparathyroidism is a common endocrine disorder of calcium metabolism
characterised by hypercalcaemia and elevated or inappropriately normal concentrations of …

Vitamin D—effects on skeletal and extraskeletal health and the need for supplementation

M Wacker, MF Holick - Nutrients, 2013 - mdpi.com
Vitamin D, the sunshine vitamin, has received a lot of attention recently as a result of a
meteoric rise in the number of publications showing that vitamin D plays a crucial role in a …

Primary hyperparathyroidism

JP Bilezikian, NE Cusano, AA Khan, JM Liu… - Nature reviews Disease …, 2016 - nature.com
Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone
(PTH) is excessively secreted from one or more of the four parathyroid glands. A single …

The anti-inflammatory effects of vitamin D in tumorigenesis

W Liu, L Zhang, HJ Xu, Y Li, CM Hu, JY Yang… - International journal of …, 2018 - mdpi.com
In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …

[HTML][HTML] From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health

AW Norman - The American journal of clinical nutrition, 2008 - Elsevier
New knowledge of the biological and clinical importance of the steroid hormone 1α, 25-
dihydroxyvitamin D 3 [1α, 25 (OH) 2 D 3] and its receptor, the vitamin D receptor (VDR), has …

Estimates of optimal vitamin D status

B Dawson-Hughes, RP Heaney, MF Holick… - Osteoporosis …, 2005 - Springer
Vitamin D has captured attention as an important determinant of bone health, but there is no
common definition of optimal vitamin D status. Herein, we address the question: What is the …

Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D

AV Krishnan, D Feldman - Annual review of pharmacology and …, 2011 - annualreviews.org
Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an
anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro …

Understanding vitamin D metabolism in pregnancy: From physiology to pathophysiology and clinical outcomes

SN Karras, CL Wagner, VD Castracane - Metabolism, 2018 - Elsevier
This critical time frame of intrauterine life development is considered of major importance on
the metabolic imprinting of overall health of the offspring, in later life. This requires a delicate …

Vitamin D and the elderly

L Mosekilde - Clinical endocrinology, 2005 - Wiley Online Library
This review summarizes current knowledge on vitamin D status in the elderly with special
attention to definition and prevalence of vitamin D insufficiency and deficiency, relationships …