Structural biology of SARS-CoV-2: open the door for novel therapies
W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …
[HTML][HTML] Role of structural and non-structural proteins and therapeutic targets of SARS-CoV-2 for COVID-19
Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
[HTML][HTML] New opportunities and challenges of natural products research: When target identification meets single-cell multiomics
Y Zhu, Z Ouyang, H Du, M Wang, J Wang, H Sun… - … Pharmaceutica Sinica B, 2022 - Elsevier
Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …
[HTML][HTML] Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19
Coronavirus disease 2019 is a newly emerging infectious disease currently spreading
across the world. It is caused by a novel coronavirus, severe acute respiratory syndrome …
across the world. It is caused by a novel coronavirus, severe acute respiratory syndrome …
The natural history, pathobiology, and clinical manifestations of SARS-CoV-2 infections
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
coronavirus disease 2019 (COVID-19). SARS-CoV-2, is a positive-sense single-stranded …
coronavirus disease 2019 (COVID-19). SARS-CoV-2, is a positive-sense single-stranded …
The SARS-CoV-2 main protease as drug target
The unprecedented pandemic of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is threatening global health. The virus emerged in late 2019 and can cause a …
(SARS-CoV-2) is threatening global health. The virus emerged in late 2019 and can cause a …
[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach
The sudden emergence of severe respiratory disease, caused by a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently become a public health …
Drug repurposing approach to fight COVID-19
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …
Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020)
Background There are many pharmacologic therapies that are being used or considered for
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated …
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the current coronavirus disease 2019 (COVID-19) pandemic. A major virulence factor of …
the current coronavirus disease 2019 (COVID-19) pandemic. A major virulence factor of …