Intrahepatic cholangiocarcinoma: epidemiology, risk factors, diagnosis and surgical management

H Zhang, T Yang, M Wu, F Shen - Cancer letters, 2016 - Elsevier
Intrahepatic cholangiocarcinoma (ICC), the least common form of cholangiocarcinomas, is a
rare hepatobiliary malignancy that arises from the epithelial cells of the intrahepatic bile …

Association of diabetes mellitus and cholangiocarcinoma: update of evidence and the effects of antidiabetic medication

C Saengboonmee, W Seubwai, W Lert-Itthiporn… - Canadian Journal of …, 2021 - Elsevier
Diabetes mellitus (DM) is a risk factor for cancer in many organs and associated with an
increased risk of cholangiocarcinoma (CCA). The molecular linkage between these …

Novel drug candidate prediction for intrahepatic cholangiocarcinoma via hub gene network analysis and connectivity mapping

Y Xiao, B Zhang, JM Cloyd, L Alaimo, G Xu, S Du… - Cancers, 2022 - mdpi.com
Simple Summary Only about 15% of intrahepatic cholangiocarcinoma (ICC) patients meet
the criteria for resection at the time of diagnosis. For patients with advanced and/or …

Surgical management of intrahepatic cholangiocarcinoma in patients with cirrhosis: impact of lymphadenectomy on peri-operative outcomes

F Bagante, G Spolverato, M Weiss… - World journal of …, 2018 - Springer
Background The consequences of lymphadenectomy (LND) on cirrhotic patients undergoing
hepatectomy for intrahepatic cholangiocarcinoma (ICC) have not been investigated. We …

Inflammatory markers in intrahepatic cholangiocarcinoma: Effects of advanced liver disease

CM Sellers, J Uhlig, JM Ludwig, SM Stein… - Cancer …, 2019 - Wiley Online Library
Background To investigate the neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte
ratio (PLR), and systemic immune‐inflammation index (SII) as prognostic biomarkers in …

A comprehensive public health conceptual framework and strategy to effectively combat cholangiocarcinoma in Thailand

N Khuntikeo, W Loilome, B Thinkhamrop… - PLoS Neglected …, 2016 - journals.plos.org
Cholangiocarcinoma (CCA) continues to occur with an exceptionally high incidence in the
northeast of Thailand, where it causes high levels of morbidity and mortality in the affected …

Steatotic liver disease among lean and non-lean individuals in Southern Lao PDR: a cross-sectional study of risk factors

A Homsana, P Southisavath, K Kling… - Annals of …, 2024 - Taylor & Francis
Background Steatotic liver disease (SLD) prevalence is rising worldwide, linked to insulin
resistance and obesity. SLD prevalence can surpass 10% even among those with normal …

Clinical risk scoring for predicting non‐alcoholic fatty liver disease in metabolic syndrome patients (NAFLD‐MS score)

S Saokaew, S Kanchanasuwan… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Non‐alcoholic fatty liver disease (NAFLD) can progress from
simple steatosis to hepatocellular carcinoma. None of tools have been developed …

Hes1 Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma

T Matsumori, Y Kodama, A Takai, M Shiokawa… - Cancer Research, 2020 - AACR
Intrahepatic cholangiocarcinoma (ICC) is frequently driven by aberrant KRAS activation and
develops in the liver with chronic inflammation. Although the Notch signaling pathway is …

Unresectable intrahepatic cholangiocarcinoma: multiparametric MR imaging to predict patient survival

A Pandey, P Pandey, M Aliyari Ghasabeh… - Radiology, 2018 - pubs.rsna.org
Purpose To determine the performance of magnetic resonance (MR) imaging–based tumor
metrics for evaluation of response to transarterial chemoembolization (TACE) in patients …