Apical periodontitis has a microbial aetiology and is one of the most common inflammatory
diseases that affect humans. Fungi, archaea and viruses have been found in association …

The oral cavity is the habitat of several hundreds of microbial taxa that have evolved to
coexist in multispecies communities in this unique ecosystem. By contrast, the internal tissue …

Evidence shows the polymicrobial etiology of endodontic infections, in which bacteria and
their products are the main agents for the development, progression, and dissemination of …

Although fungi, archaea, and viruses contribute to the microbial diversity in endodontic
infections, bacteria are the most common micro-organisms occurring in these infections …

Acute apical abscess is the most common form of dental abscess and is caused by infection
of the root canal of the tooth. It is usually localized intraorally, but in some cases the apical …

Bacteria have been implicated in the pathogenesis and progression of pulp and periapical
diseases. The primary aim of endodontic treatment is to remove as many bacteria as …

Endodontic disease is a biofilm-mediated infection, and primary aim in the management of
endodontic disease is the elimination of bacterial biofilm from the root canal system. The …

Effective management of biofilm‐related oral infectious diseases is a global challenge. Oral
biofilm presents increased resistance to antimicrobial agents and elevated virulence …

Next‐generation sequencing (NGS) has now been applied for a decade to characterize the
microbiota composition of infected dental root canals associated with apical periodontitis …

Introduction This study compared the clinical and radiographic outcome of endodontic
retreatment of teeth with apical periodontitis using either 1% sodium hypochlorite (NaOCl) or …