In recent years, neonicotinoids have been the fastest‐growing class of insecticides in
modern crop protection, with widespread use against a broad spectrum of sucking and …

Until the mid-20th century, pest insect control in agriculture relied on largely inorganic and
botanical insecticides, which were inadequate. Then, the remarkable insecticidal properties …

Nicotinic acid adenine dinucleotide phosphate (NAADP) is an agonist-generated second
messenger that releases Ca 2+ from intracellular acidic Ca 2+ stores. Recent evidence has …

Acetylcholine-binding proteins (AChBPs) from mollusks are suitable structural and functional
surrogates of the nicotinic acetylcholine receptors when combined with transmembrane …

As a result of recent developments in molecular biology, the investigation of biofunctional
machinery at ligand‐accepting interfaces has become one of the challenging and important …

Five pyridine derivatives, namely, N-morpholinium 7, 7-dimethyl-3-cyano-4-(4′-nitrophenyl)-
5-oxo-1, 4, 5, 6, 7, 8-hexahydroquinoline-2-thiolate (1), sodium 5-acetyl-3-amino-4-(4 …

The work included in this paper involves the synthesis of thirteen heterocyclic compounds,
piperidinium and morpholinium 3-cyanopyridinethiolates 5–14, 17, 20 and 21 in our Lab …

A novel chemotype insecticide flupyrimin (FLP)[N-[(E)-1-(6-chloro-3-pyridinylmethyl) pyridin-
2 (1 H)-ylidene]-2, 2, 2-trifluoroacetamide], discovered by Meiji Seika Pharma, has unique …

The nicotinic acetylcholine (ACh) receptor (nAChR) plays a crucial role in excitatory
neurotransmission and is an important target for drugs and insecticides. Diverse nAChR …

(2 S, 3 R)-N-[2-(Pyridin-3-ylmethyl)-1-azabicyclo [2.2. 2] oct-3-yl] benzo [b] furan-2-
carboxamide (7a, TC-5619), a novel selective agonist of the α7 neuronal nicotinic …