Endocytosis in cancer and cancer therapy

B Banushi, SR Joseph, B Lum, JJ Lee… - Nature Reviews …, 2023 - nature.com
Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Role of B cells as antigen presenting cells

I Rastogi, D Jeon, JE Moseman, A Muralidhar… - Frontiers in …, 2022 - frontiersin.org
B cells have been long studied for their role and function in the humoral immune system.
Apart from generating antibodies and an antibody-mediated memory response against …

[HTML][HTML] Predictability of B cell clonal persistence and immunosurveillance in breast cancer

SJ Sammut, JD Galson, R Minter, B Sun, SF Chin… - Nature …, 2024 - nature.com
B cells and T cells are important components of the adaptive immune system and mediate
anticancer immunity. The T cell landscape in cancer is well characterized, but the …

B-cell receptor signaling and beyond: the role of Igα (CD79a)/Igβ (CD79b) in normal and malignant B cells

A Tkachenko, K Kupcova, O Havranek - International Journal of …, 2023 - mdpi.com
B-cell receptor (BCR) is a B cell hallmark surface complex regulating multiple cellular
processes in normal as well as malignant B cells. Igα (CD79a)/Igβ (CD79b) are essential …

Potential pathogenic impact of cow's milk consumption and bovine milk-derived exosomal MicroRNAs in diffuse large B-Cell lymphoma

BC Melnik, R Stadler, R Weiskirchen… - International Journal of …, 2023 - mdpi.com
Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

Correlation of Professional Antigen‐Presenting Tbet+CD11c+ B Cells With Bone Destruction in Untreated Rheumatoid Arthritis

S McGrath, K Grimstad, K Thorarinsdottir… - Arthritis & …, 2024 - Wiley Online Library
Objective Subsets of CD21−/low memory B cells (MBCs), including double‐negative (DN,
CD27− IgD−) and Tbet+ CD11c+ cells, are expanded in chronic inflammatory diseases. In …

The transcriptional program during germinal center reaction-a close view at GC B cells, Tfh cells and Tfr cells

AC Betzler, A Ushmorov, C Brunner - Frontiers in Immunology, 2023 - frontiersin.org
The germinal center (GC) reaction is a key process during an adaptive immune response to
T cell specific antigens. GCs are specialized structures within secondary lymphoid organs, in …

Endolysosomal vesicles at the center of B cell activation

S Hämälistö, F Del Valle Batalla, MI Yuseff… - Journal of Cell …, 2024 - rupress.org
The endolysosomal system specializes in degrading cellular components and is crucial to
maintaining homeostasis and adapting rapidly to metabolic and environmental cues. Cells …

Biology of endophilin and it's role in disease

LQ Yang, AF Huang, WD Xu - Frontiers in Immunology, 2023 - frontiersin.org
Endophilin is an evolutionarily conserved family of protein that involves in a range of
intracellular membrane dynamics. This family consists of five isoforms, which are distributed …

Correlation of Professional Antigen-Presenting Tbet+ CD11c+ B Cells With Bone Destruction in Untreated Rheumatoid Arthritis

S McGrath, K Grimstad, K Thorarinsdottir… - Arthritis & …, 2024 - diva-portal.org
Objective: Subsets of CD21−/low memory B cells (MBCs), including double-negative (DN,
CD27− IgD−) and Tbet+ CD11c+ cells, are expanded in chronic inflammatory diseases. In …