An organocatalyzed asymmetric Michael addition reaction has been established as the most
relevant and dynamic research area for the construction of chiral carbon‐carbon and carbon …

Both syn‐and anti‐β‐amino alcohols are common structural motifs in natural products, drug
molecules, chiral ligands and catalysts. However, the currently available methods for …

In 1971, chemists from Hoffmann-La Roche and Schering AG independently discovered a
new asymmetric intramolecular aldol reaction catalyzed by the natural amino acid proline, a …

Organocatalytic conjugate addition reactions of aldehydes to fluoroalkylated nitroolefins with
chiral amine catalysts offer a straightforward stereoselective path to fluoroalkylated γ …

The catalytic kinetic resolution of racemic β-branched aldehydes offers a straightforward
stereoselective entry to aldehydes and addition products. Yet, control over stereoselectivity …

Peptides have been established as modular catalysts for various transformations. Still, the
vast number of potential amino acid building blocks renders the identification of peptides …

Trifluoromethylsulfones (triflones) are useful compounds for synthesis and beyond. Yet,
methods to access chiral triflones are scarce. Here, we present a mild and efficient …

The enantioselective total synthesis of madangamine E has been completed in 30 steps,
enabled by a new catalytic and highly enantioselective desymmetrizing intramolecular …

N‐heterocyclic moieties are abundant among pharmaceuticals and agrochemicals, but a
challenge for metalorganic and organocatalytic transformations. We present tripeptides of …

Catalytic stereoselective additions with maleimides are useful one‐step reactions to yield
chiral succinimides, molecules that are widespread among therapeutically active …