Predictive metabolites for incident myocardial infarction: a two-step meta-analysis of individual patient data from six cohorts comprising 7897 individuals from the …
Aims Myocardial infarction (MI) is a major cause of death and disability worldwide. Most
metabolomics studies investigating metabolites predicting MI are limited by the participant …
metabolomics studies investigating metabolites predicting MI are limited by the participant …
Estimating additive interaction in two-stage individual participant data meta-analysis
M Basten, LA van Tuijl, KY Pan… - American Journal of …, 2024 - academic.oup.com
Individual participant data (IPD) meta-analysis provides important opportunities to study
interaction and effect modification for which individual studies often lack power. While …
interaction and effect modification for which individual studies often lack power. While …
[HTML][HTML] Nonlinear effects and effect modification at the participant-level in IPD meta-analysis part 2: methodological guidance is available
Objectives To review methodological guidance for nonlinear covariate-outcome
associations (NL), and linear effect modification and nonlinear effect modification (LEM and …
associations (NL), and linear effect modification and nonlinear effect modification (LEM and …
Individual participant data meta‐analysis to examine linear or non‐linear treatment‐covariate interactions at multiple time‐points for a continuous outcome
M Hattle, J Ensor, K Scandrett… - Research Synthesis …, 2024 - Wiley Online Library
Individual participant data (IPD) meta‐analysis projects obtain, harmonise, and synthesise
original data from multiple studies. Many IPD meta‐analyses of randomised trials are …
original data from multiple studies. Many IPD meta‐analyses of randomised trials are …
Examining non-linear effects and effect modification in IPD meta-analysis part 2: guidance is available
ObjectivesTo review methodological guidance for non-linear associations (NL), and linear
and non-linear effect modification (LEM and NLEM) in individual participant data meta …
and non-linear effect modification (LEM and NLEM) in individual participant data meta …