Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

Cyclopropanol and its derivatives are carbocyclic homologues of enols, and there is an
obvious similarity in chemical properties between these classes of compounds due to the …

Methylene-and alkylidenecyclopropanes (MCPs and ACPs, 1, Figure 1) and-cyclobutanes
(MCBs and ACBs, 2, Figure 1) are highly strained molecules, but at the same time most of …

Heterocyclic compounds, which represent almost two-thirds of all the known organic
compounds, include some of the most significant for human beings. It is not surprising …

Nitroalkanes and nitroalkenes have been always considered as convenient and readily
available intermediates in organic synthesis, including total synthesis of natural products. 1 …

Cycloadditions are known to be one of the most abundant, versatile and valuable classes of
chemical reactions. Among various efficient chemical processes, cycloaddition is an …

Cyclopropanols are readily available via the Kulinkovich cyclopropanation, the Simmons-
Smith reaction, and other synthetic methods. Due to their intrinsic ring stains, cyclopropanols …

Plants of the species Gelsemium have found application in traditional Asian medicine for
over a thousand years. Gelsemoxonine represents a novel constituent of this plant …

Asymmetric 1, 3-dipolar [2+ 3] cycloadditions (Z,% DCA) are reactions involving a I, 3-dipole
and a dipolarophile. The dipole is a 4n-system (an ylide) and the dipolarophile is a 2n …

Gelsemoxonine (1) is a Gelsemium alkaloid incorporating an unusual azetidine. Its total
synthesis was achieved employing a novel ring contraction of a spirocyclopropane …