[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
[HTML][HTML] Toward a global virus genomic surveillance network
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …
its utility for public health. Now, we must harness the momentum that led to increased …
Urbanization and humidity shape the intensity of influenza epidemics in US cities
Influenza epidemics vary in intensity from year to year, driven by climatic conditions and by
viral antigenic evolution. However, important spatial variation remains unexplained. Here we …
viral antigenic evolution. However, important spatial variation remains unexplained. Here we …
Metagenomic nanopore sequencing of influenza virus direct from clinical respiratory samples
Influenza is a major global public health threat as a result of its highly pathogenic variants,
large zoonotic reservoir, and pandemic potential. Metagenomic viral sequencing offers the …
large zoonotic reservoir, and pandemic potential. Metagenomic viral sequencing offers the …
Towards a universal influenza vaccine: different approaches for one goal
GA Sautto, GA Kirchenbaum, TM Ross - Virology journal, 2018 - Springer
Influenza virus infection is an ongoing health and economic burden causing epidemics with
pandemic potential, affecting 5–30% of the global population annually, and is responsible …
pandemic potential, affecting 5–30% of the global population annually, and is responsible …
Population immunity predicts evolutionary trajectories of SARS-CoV-2
The large-scale evolution of the SARS-CoV-2 virus has been marked by rapid turnover of
genetic clades. New variants show intrinsic changes, notably increased transmissibility, and …
genetic clades. New variants show intrinsic changes, notably increased transmissibility, and …
Steering and controlling evolution—from bioengineering to fighting pathogens
M Lässig, V Mustonen, A Nourmohammad - Nature Reviews Genetics, 2023 - nature.com
Control interventions steer the evolution of molecules, viruses, microorganisms or other cells
towards a desired outcome. Applications range from engineering biomolecules and …
towards a desired outcome. Applications range from engineering biomolecules and …
Projecting the SARS-CoV-2 transition from pandemicity to endemicity: Epidemiological and immunological considerations
In this review, we discuss the epidemiological dynamics of different viral infections to project
how the transition from a pandemic to endemic Severe Acute Respiratory Syndrome …
how the transition from a pandemic to endemic Severe Acute Respiratory Syndrome …
The WHO global influenza surveillance and response system (GISRS)—a future perspective
AJ Hay, JW McCauley - Influenza and other respiratory viruses, 2018 - Wiley Online Library
In the centenary year of the devastating 1918‐19 pandemic, it seems opportune to reflect on
the success of the WHO Global Influenza Surveillance and Response System (GISRS) …
the success of the WHO Global Influenza Surveillance and Response System (GISRS) …
[HTML][HTML] Childhood immune imprinting to influenza A shapes birth year-specific risk during seasonal H1N1 and H3N2 epidemics
Across decades of co-circulation in humans, influenza A subtypes H1N1 and H3N2 have
caused seasonal epidemics characterized by different age distributions of cases and …
caused seasonal epidemics characterized by different age distributions of cases and …