Females have increased pain sensitivity and are more vulnerable to chronic pain conditions.
Sleep disturbances are comorbid with chronic pain and exacerbate pain symptoms. Different …

Background: Fibromyalgia (FM) is a chronic pain disease characterized by multiple
symptoms whose interactions and implications in the disease pathology are still unclear …

Introduction Drivers should be aware of possible impairing effects of alcohol, medicinal
substance, or fatigue on driving performance. Such effects are assessed in clinical trials …

Aim We assessed whether total sleep deprivation (TSD) in combination with pain tests yields
a reliable method to assess altered pain thresholds, which subsequently may be used to …

In behavioral and neurophysiological pain studies, multiple types of calibration methods are
used to quantify the individual pain sensation stimuli. Often, studies lack a detailed …

Recently, methods have been developed enabling the characterization of the nociceptive
function at the detection threshold level by measuring nociceptive detection thresholds …

Diagnosis and stratification of small-fiber neuropathy patients is difficult due to a lack of
methods that are both sensitive and specific. Our lab recently developed a method to …

Background Perceptual thresholds are measured in scientific and clinical setting to evaluate
performance of the nervous system in essential tasks such as vision, hearing, touch, and …

Drivers should be aware of possible impairing effects of alcohol, medicinal substance, or
fatigue on driving performance. Such effects are assessed in clinical trials, including a …

REsulTs Mexiletine significantly increased cold pressor pain tolerance (Estimate of
Difference (ED): 10.5%; p=. 03), and altered affective cold pain perception (ED:-0.13, p …