Nutrient vitamins enabled metabolic regulation of ferroptosis via reactive oxygen species biology
J Wu, Y Shi, M Zhou, M Chen, S Ji, X Liu… - Frontiers in …, 2024 - frontiersin.org
Vitamins are dietary components necessary for cellular metabolic balance, especially redox
homeostasis; deficient or excessive supply may give rise to symptoms of psychiatric …
homeostasis; deficient or excessive supply may give rise to symptoms of psychiatric …
Immunomodulation of cuproptosis and ferroptosis in liver cancer
J Mo, S Zhang, Q Li, M Chen, Y Zheng, X Xie… - Cancer Cell …, 2024 - Springer
According to statistics, the incidence of liver cancer is increasing yearly, and effective
treatment of liver cancer is imminent. For early liver cancer, resection surgery is currently the …
treatment of liver cancer is imminent. For early liver cancer, resection surgery is currently the …
[HTML][HTML] Hypoxia‐inducible factor‐1α can reverse the Adriamycin resistance of breast cancer adjuvant chemotherapy by upregulating transferrin receptor and …
X Yu, Q Guo, H Zhang, X Wang, Y Han… - The FASEB …, 2024 - pmc.ncbi.nlm.nih.gov
Breast cancer is a common malignant tumor in women. Ferroptosis, a programmed cell
death pathway, is closely associated with breast cancer and its resistance. The transferrin …
death pathway, is closely associated with breast cancer and its resistance. The transferrin …
Iron-dependent KDM4D activity controls the quiescence-activity balance of MSCs via the PI3K-Akt-Foxo1 pathway
Z Xie, Y Che, G Huang, Z Su, J Lin, G Zheng… - Cellular and Molecular …, 2024 - Springer
Iron deficiency is a prevalent nutritional deficit associated with organ damage and
dysfunction. Recent research increasingly associates iron deficiency with bone metabolism …
dysfunction. Recent research increasingly associates iron deficiency with bone metabolism …
Integrating multi-omics techniques and in vitro experiments reveals that GLRX3 regulates the immune microenvironment and promotes hepatocellular carcinoma cell …
Y Li, Y Chen, Y Zhang, Y Fang, L Wu, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a common malignancy worldwide, and its
development is closely related to abnormalities in iron metabolism. This study aims to …
development is closely related to abnormalities in iron metabolism. This study aims to …
[HTML][HTML] Enhancer of Zeste Homolog 2 Protects Mucosal Melanoma from Ferroptosis via the KLF14-SLC7A11 Signaling Pathway
H Du, L Hou, H Yu, F Zhang, K Tong, X Wu, Z Zhang… - Cancers, 2024 - mdpi.com
Background: Mucosal melanoma (MM) is epidemiologically, biologically, and molecularly
distinct from cutaneous melanoma. Current treatment strategies have failed to significantly …
distinct from cutaneous melanoma. Current treatment strategies have failed to significantly …
KLF14 directly downregulates the expression of GPX4 to exert antitumor effects by promoting ferroptosis in cervical cancer
H Ye, XC Ding, XR Lv, Y Du, R Guo, J Qiu… - Journal of Translational …, 2024 - Springer
Background Cervical cancer is the fourth leading cause of cancer-related death among
women worldwide, and effective therapeutic strategies for its treatment are limited. Recent …
women worldwide, and effective therapeutic strategies for its treatment are limited. Recent …
[HTML][HTML] HEPPAR1 and PIWIL2 as Panel Markers for Hepatocellular Carcinoma
G Hammad, M Magdy, T Aboushousha… - … Pacific Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objective: The aim of this study was to evaluate the expression profiles of PIWI-like protein-2
(PIWIL2), and HepPar1 and their immunohistochemical (IHC) characteristics in …
(PIWIL2), and HepPar1 and their immunohistochemical (IHC) characteristics in …
Molecular mechanism of WWP1‐mediated ubiquitination modification affecting proliferation and invasion/migration of liver cancer cells
C Zhang, W Wang, B Wu - The Kaohsiung Journal of Medical …, 2024 - Wiley Online Library
Liver cancer is the most prevalent fatal malignancy across the globe. The present study aims
to explore the molecular mechanism of E3 ligase WWP1 in liver cancer cell proliferation and …
to explore the molecular mechanism of E3 ligase WWP1 in liver cancer cell proliferation and …
Prognostic Significance of Iron Metabolism and Immune-Related Genes as Risk Markers in Hepatocellular Carcinoma
S Tang, H Chen - Journal of Environmental Pathology …, 2024 - dl.begellhouse.com
Hepatocellular carcinoma (HCC) is a highly lethal liver cancer with significant heterogeneity,
which poses challenges in predicting prognosis and treatment outcomes. The impact of iron …
which poses challenges in predicting prognosis and treatment outcomes. The impact of iron …