[HTML][HTML] The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

I Ullah, G Beaudoin-Bussières, K Symmes… - Cell Reports …, 2023 - cell.com
Summary COVID-19 convalescent plasmas (CCPs) are chosen for plasma therapy based on
neutralizing titers and anti-Spike immunoglobulin levels. However, CCP characteristics that …

Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines

P Kaplonek, Y Deng, JSL Lee, HJ Zar, D Zavadska… - Cell Reports …, 2023 - cell.com
Despite the successes of current coronavirus disease 2019 (COVID-19) vaccines, waning
immunity, the emergence of variants of concern, and breakthrough infections among …

Antibody-dependent cellular cytotoxicity against SARS-CoV-2 Omicron sub-lineages is reduced in convalescent sera regardless of infecting variant

SI Richardson, P Kgagudi, NP Manamela… - Cell Reports …, 2023 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA. 4 and BA.
5 variants caused major waves of infections. Here, we assess the sensitivity of BA. 4 to …

Shared N417-dependent epitope on the SARS-CoV-2 omicron, beta, and delta plus variants

T Moyo-Gwete, M Madzivhandila, NN Mkhize… - Journal of …, 2022 - Am Soc Microbiol
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve,
several variants of concern (VOCs) have arisen which are defined by multiple mutations in …

[HTML][HTML] Humoral immune responses against SARS-CoV-2 Spike variants after mRNA vaccination in solid organ transplant recipients

A Tauzin, G Beaudoin-Bussières, SY Gong… - Iscience, 2022 - cell.com
Summary Although SARS-CoV-2 mRNA vaccination has been shown to be safe and
effective in the general population, immunocompromised solid organ transplant recipients …

SARS-CoV-2 BA. 4/5 infection triggers more cross-reactive FcγRIIIa signaling and neutralization than BA. 1, in the context of hybrid immunity

SI Richardson, N Mzindle, T Motlou… - Journal of …, 2024 - journals.asm.org
ABSTRACT SARS-CoV-2 variants of concern (VOCs) differentially trigger neutralizing and
antibody-dependent cellular cytotoxic (ADCC) antibodies with variable cross-reactivity …

Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants

A Banerjee, J Lew, A Kroeker, K Baid, P Aftanas… - Med, 2022 - cell.com
Summary Background SARS-CoV-2 Omicron variant of concern (VOC) has evolved multiple
mutations within the spike protein, raising concerns of increased antibody evasion. In this …

Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens

I Ullah, F Escudie, I Scandale, Z Gilani… - Iscience, 2024 - cell.com
Direct acting antivirals (DAAs) represent critical tools for combating severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have escaped …

[HTML][HTML] Ad26. COV2. S priming provided a solid immunological base for mRNA-based COVID-19 booster vaccination

D Geers, RSG Sablerolles, D van Baarle, NA Kootstra… - Iscience, 2023 - cell.com
The emergence of novel SARS-CoV-2 variants led to the recommendation of booster
vaccinations after Ad26. COV2. S priming. It was previously shown that heterologous …

Building a resilient scientific network for COVID-19 and beyond

NE Babady, RM Burckhardt, F Krammer, PL Moore… - Mbio, 2022 - Am Soc Microbiol
The continued evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
necessitates that the global scientific community monitor, assess, and respond to the …