Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy

SD Akshay, VK Deekshit, J Mohan Raj… - ACS Infectious …, 2023 - ACS Publications
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

Immunoinformatics design of multi-epitope vaccine using OmpA, OmpD and enterotoxin against non-typhoidal salmonellosis

B Beikzadeh - BMC bioinformatics, 2023 - Springer
Abstract Background Non-typhoidal Salmonella (NTS) is one of the important bacteria that
cause foodborne diseases and invasive infections in children and elderly people. Since NTS …

Immunoinformatics design of a novel multiepitope vaccine candidate against non-typhoidal salmonellosis caused by Salmonella Kentucky using outer membrane …

EE Igomu, PH Mamman, J Adamu, M Muhammad… - PloS one, 2025 - journals.plos.org
The global public health risk posed by Salmonella Kentucky (S. Kentucky) is rising,
particularly due to the dissemination of antimicrobial resistance genes in human and animal …

In silico designing and characterization of outer membrane protein (OmpC) gene from Salmonella enterica and its expression in Nicotiana tabacum for developing a …

F Ijaz, M Sameeullah, A Farid, MS Malik, N Batool… - Microbial …, 2025 - Elsevier
Salmonella, a gram-negative bacteria, is the leading cause of foodborne illness globally.
Two serovars of Salmonella, S. enteritidis and S. typhimurium are responsible for the …

[HTML][HTML] Immunoprophylactic potential of recombinant outer membrane protein of Salmonella enterica serovar Typhi against enteric fever in BALB/c mice

K Latif, S Naz, R Bashir, F Saleem, N Munir… - Journal of King Saud …, 2024 - Elsevier
Objectives This study was design to explore the immunogenic behavior of LamB and SpaO
outer membrane protein of Salmonella serovar Typhi against enteric fever in BALB/c mice …

Immunological characterization of chitosan adjuvanted outer membrane proteins of Salmonella enterica serovar Typhi as multi-epitope typhoid vaccine candidate

A Ayub, M Usman, A Ihsan, Q Ain, AB Awan… - Molecular Biology …, 2022 - Springer
Abstract Background Outer membrane proteins (OMPs) of Gram-negative bacteria have
been known as potential vaccine targets due to their antigenic properties and host …

Comparative Molecular Analysis and Antigenicity Prediction of an Outer Membrane Protein (ompC) of Non-typhoidal Salmonella Serovars Isolated from Different …

M Yusuf, A Ajayi, UU Essiet… - … and Biology Insights, 2023 - journals.sagepub.com
Non-typhoidal Salmonella (NTS) infections occur globally with high morbidity and mortality.
The public health challenge caused is exacerbated by increasing rate of antibiotic …

Improving detection and quantification of major histocompatibility complex (MHC)-presented immunopeptides for vaccine development

TC Baker - 2024 - open.library.ubc.ca
The adaptive immune system relies on antigen presentation governed by major
histocompatibility complexes (MHCs), which initiate immune responses upon recognition by …

Engineering a Recombinant Chimeric Protein Consisting of OmpL Antigen Conjugated to HBHA Molecular Adjuvant (HBHA-OmpL) with the Aim of Developing a …

M Bazgir, N Shams, A Forouharmehr… - Veterinary Research & …, 2023 - vj.areeo.ac.ir
Salmonella Typhimurium is a zoonotic gram-negative bacterium of the Enterobacteriaceae
family. One of the newest ways against the pathogen is the use of recombinant vaccines. In …

Systemic and local immune responses to Salmonella enterica serovar Typhi by prime boost strategy with different preparations of Salmonella antigen (s)

L Barai - 2021 - reposit.library.du.ac.bd
Typhoid fever, caused by Salmonella enterica serovar Typhi (Salmonella Typhi), is an
important medical and public health problem in South East Asia including Bangladesh and …