During the past few decades, supercritical fluid (SCF) has emerged as an effective
alternative for many traditional pharmaceutical manufacturing processes. Operating active …

The solubility dependent bioavailability problem has become a major hurdle in drug
development processes. Drug nanocrystals have been widely accepted by the …

Colloidal nanocarriers, in their various forms, have the possibility of providing endless
opportunities in the area of drug delivery. The current communication embodies an in-depth …

The interest in the preparation and application of nanometer size materials is increasing
since they can exhibit properties of great industrial interest. Several techniques have been …

Traditional micronization processes can be improved by taking advantage of the unique
characteristics of the supercritical antisolvents that include very large diffusivities when …

Poor water solubility is an industry wide issue, especially for pharmaceutical scientists in
drug discovery and drug development. In recent years, nanoparticle engineering processes …

The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …

The interest of the use of supercritical fluids, especially supercritical CO2, for particle
engineering over the last years has received attention from the pharmaceutical industry …

Among all newly discovered chemical entities about 40% drugs are lipophillic and fail to
reach market due to their poor aqueous solubility. For orally administered drugs solubility is …

In the recent decades, polymers are widely used as biomaterials due to their favorable
properties such as good biocompatibility, easy design and preparation, a variety of …