This article discusses points to consider when undertaking a clinical trial to test therapy for
skin ulcers in SSc. A validated definition of skin ulcers should be used if available. Defining …

Digital ulcers (DU) affect up to half of all patients with systemic sclerosis at some point during
their disease. These lesions are extremely painful, heal slowly, and lead to substantial …

Scleroderma, or systemic sclerosis (SS), is an autoimmune disease leading to ischemic
fibrosis and widespread collagen deposition, invariably affecting the hands. Optimized …

Points essentiels Les ulcères digitaux sont une manifestation fréquente de la sclérodermie
systémique. Malgré leur fréquence, il n'existe pas actuellement de consensus sur leur prise …

OBJETIVO: Estabelecer a utilidade da medida indireta da pressão venosa periférica (PVP)
na avaliação de pacientes com esclerose sistêmica (ES), comparando com uma população …

Digital vasculopathy and subsequent digital ulceration are common and painful
complications of limited cutaneous systemic sclerosis. Although the use of hydrocolloid …

Skin ulcers can be very painful and detrimental in patients with systemic sclerosis, or
systemic scleroderma. A brief review of scleroderma skin ulcers is presented, as well as a …

Background: There are a large number of studies addressing the treatment and assessment
of chronic ulcers. Despite the fact that ischemic ulcers are frequent and difficult to manage in …

Digital ulcerations (DU) are a frequent presentation and complication of systemic sclerosis
caused by sudden acute critical tissue ischaemia of the upper and or lower limb extremities …

SYSTEMIC SCLEROSIS is a chronic disease resulting from a self-sustaining cycle of
inflammation, vascular damage, fibroblast proliferation, intraluminal thrombosis, vasospasm …