Polyprodrug nanomedicines: an emerging paradigm for cancer therapy

K Yang, Z Yang, G Yu, Z Nie, R Wang… - Advanced …, 2022 - Wiley Online Library
Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …

Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy

XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials Advances, 2022 - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Pathway-controlled aqueous supramolecular polymerization via solvent-dependent chain conformation effects

L Borsdorf, L Herkert, N Bäumer… - Journal of the …, 2023 - ACS Publications
Solute–solvent interactions play a critical role in multiple fields, including biology, materials
science, and (physical) organic, polymer, and supramolecular chemistry. Within the growing …

Size Optimization of Organic Nanoparticles with Aggregation‐Induced Emission Characteristics for Improved ROS Generation and Photodynamic Cancer Cell Ablation

S Gan, W Wu, G Feng, Z Wang, B Liu, BZ Tang - Small, 2022 - Wiley Online Library
Aggregation‐induced emission (AIE) fluorogens provide new opportunities to promote
efficient reactive oxygen species (ROS) production in aggregates, which represent the …

[HTML][HTML] A supramolecular nanoplatform for imaging-guided phototherapies via hypoxia tumour microenvironment remodeling

W Zhou, S Chen, Y Ouyang, B Huang, H Zhang… - Chemical …, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) has emerged as an invasive and promising antitumour
treatment, however, the hypoxia in deep tumour tissues and the poor water-solubility of …

[HTML][HTML] Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems

M Komiyama - Beilstein Journal of Nanotechnology, 2023 - beilstein-journals.org
Cyclodextrins have been widely employed for drug delivery systems (DDSs) in which drugs
are selectively delivered to a target site in the body. Recent interest has been focused on the …

Controllable singlet oxygen generation in water based on cyclodextrin secondary assembly for targeted photodynamic therapy

X Dai, X Dong, Z Liu, G Liu, Y Liu - Biomacromolecules, 2020 - ACS Publications
The construction of supramolecular assembly whose singlet oxygen (1O2) generation
capability can be controllably regulated in water still remains challenging. Herein, a novel …

Mitochondria-targeting and ROS-sensitive smart nanoscale supramolecular organic framework for combinational amplified photodynamic therapy and chemotherapy

J Tian, B Huang, Z Cui, P Wang, S Chen, G Yang… - Acta Biomaterialia, 2021 - Elsevier
Owing to their reversibly dynamic features, and the regularity of their architectures,
supramolecular organic frameworks (SOFs) have attracted attention as new porous …

A novel photoswitchable AIE-active supramolecular photosensitizer with synergistic enhancement of ROS-generation ability constructed by a two-step sequential …

X Tian, S Li, K Velmurugan, Z Bai, Q Liu… - Materials Chemistry …, 2023 - pubs.rsc.org
Photosensitizers (PSs), featuring switchable properties to achieve tunable reactive oxygen
species (ROS) generation, are highly desirable in photodynamic treatment and antibacterial …

Organic/inorganic supramolecular nano-systems based on host/guest interactions

X Yang, D Yuan, J Hou, AC Sedgwick, S Xu… - Coordination Chemistry …, 2021 - Elsevier
Since the first demonstration of synthetic host/guest chemistry, the area of supramolecular
chemistry has rapidly expanded and become highly influential in the areas of biomedicine …