Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies

D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …

Brain imaging in Alzheimer disease

KA Johnson, NC Fox… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past
four decades. Initially, computed tomography (CT) and then magnetic resonance imaging …

Functional alterations in memory networks in early Alzheimer's disease

RA Sperling, BC Dickerson, M Pihlajamaki… - Neuromolecular …, 2010 - Springer
The hallmark clinical symptom of early Alzheimer's disease (AD) is episodic memory
impairment. Recent functional imaging studies suggest that memory function is subserved …

Reduced grid-cell–like representations in adults at genetic risk for Alzheimer's disease

L Kunz, TN Schröder, H Lee, C Montag, B Lachmann… - Science, 2015 - science.org
Alzheimer's disease (AD) manifests with memory loss and spatial disorientation. AD
pathology starts in the entorhinal cortex, making it likely that local neural correlates of spatial …

[HTML][HTML] The effect of alcohol consumption on the adolescent brain: A systematic review of MRI and fMRI studies of alcohol-using youth

SWF Ewing, A Sakhardande, SJ Blakemore - NeuroImage: Clinical, 2014 - Elsevier
Background A large proportion of adolescents drink alcohol, with many engaging in high-
risk patterns of consumption, including binge drinking. Here, we systematically review and …

Neuropsychological and neuroimaging changes in preclinical Alzheimer's disease

EW Twamley, SAL Ropacki, MW Bondi - Journal of the International …, 2006 - cambridge.org
Alzheimer's disease (AD) is a common, devastating form of dementia. With the advent of
promising symptomatic treatment, the importance of recognizing AD at its very earliest …

Effect of APOE ε4 status on intrinsic network connectivity in cognitively normal elderly subjects

MM Machulda, DT Jones, P Vemuri… - Archives of …, 2011 - jamanetwork.com
Objective To examine default mode and salience network functional connectivity as a
function ofAPOEε4 status in a group of cognitively normal age-, sex-, and education …

Neuropsychological contributions to the early identification of Alzheimer's disease

MW Bondi, AJ Jak, L Delano-Wood… - Neuropsychology …, 2008 - Springer
A wealth of evidence demonstrates that a prodromal period of Alzheimer's disease (AD)
exists for some years prior to the appearance of significant cognitive and functional declines …

Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups

AS Fleisher, A Sherzai, C Taylor, JBS Langbaum… - Neuroimage, 2009 - Elsevier
To assess the ability of resting-state functional magnetic resonance imaging to distinguish
known risk factors for AD, we evaluated 17 cognitively normal individuals with a family …

The potential of functional MRI as a biomarker in early Alzheimer's disease

R Sperling - Neurobiology of aging, 2011 - Elsevier
Functional magnetic resonance imaging (fMRI) is a relative newcomer in the field of
biomarkers for Alzheimer's disease (AD). fMRI has several potential advantages, particularly …