Morris water maze: a versatile and pertinent tool for assessing spatial learning and memory
Since its development about 40 years ago (1981–2021), Morris water maze has turned into
a very popular tool for assessing spatial learning and memory. Its many advantages have …
a very popular tool for assessing spatial learning and memory. Its many advantages have …
Assessment of spatial memory in mice
S Sharma, S Rakoczy, H Brown-Borg - Life sciences, 2010 - Elsevier
Improvements in health care have greatly increased life span in the United States. The focus
is now shifting from physical well-being to improvement in mental well-being or maintenance …
is now shifting from physical well-being to improvement in mental well-being or maintenance …
Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in mice
J Knoferle, SY Yoon, D Walker, L Leung… - Journal of …, 2014 - Soc Neuroscience
Apolipoprotein (apo) E4 is expressed in many types of brain cells, is associated with age-
dependent decline of learning and memory in humans, and is the major genetic risk factor …
dependent decline of learning and memory in humans, and is the major genetic risk factor …
Spatial navigation is distinctively impaired in persistent postural perceptual dizziness
HA Breinbauer, MD Contreras, JP Lira… - Frontiers in …, 2020 - frontiersin.org
Objective: To determine whether performance in a virtual spatial navigational task is poorer
in persistent postural perceptual dizziness (PPPD) patients than in healthy volunteers and …
in persistent postural perceptual dizziness (PPPD) patients than in healthy volunteers and …
Pathfinder: open source software for analyzing spatial navigation search strategies
Spatial navigation is a universal behavior that varies depending on goals, experience and
available sensory stimuli. Spatial navigational tasks are routinely used to study learning …
available sensory stimuli. Spatial navigational tasks are routinely used to study learning …
The water maze paradigm in experimental studies of chronic cognitive disorders: Theory, protocols, analysis, and inference
An instrumental step in assessing the validity of animal models of chronic cognitive
disorders is to document disease-related deficits in learning/memory capacity. The water …
disorders is to document disease-related deficits in learning/memory capacity. The water …
[HTML][HTML] Protective effect of α-terpineol against impairment of hippocampal synaptic plasticity and spatial memory following transient cerebral ischemia in rats
Objective (s): Cerebral ischemia is often associated with cognitive impairment. Oxidative
stress has a crucial role in the memory deficit following ischemia/reperfusion injury. α …
stress has a crucial role in the memory deficit following ischemia/reperfusion injury. α …
[HTML][HTML] Pupillary responses and memory-guided visual search reveal age-related and Alzheimer's-related memory decline
MC Dragan, TK Leonard, AM Lozano… - Behavioural Brain …, 2017 - Elsevier
Episodic memory–composed of memory for unique spatiotemporal experiences–is known to
decline with aging, and even more severely in Alzheimer's disease (AD). Memory for trial …
decline with aging, and even more severely in Alzheimer's disease (AD). Memory for trial …
Value-complexity tradeoff explains mouse navigational learning
We introduce a novel methodology for describing animal behavior as a tradeoff between
value and complexity, using the Morris Water Maze navigation task as a concrete example …
value and complexity, using the Morris Water Maze navigation task as a concrete example …
A concomitant bone fracture delays cognitive recovery from traumatic brain injury
Y Suto, K Nagata, SM Ahmed… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND Brain injury progression after severe traumatic brain injury (TBI) is
associated with worsening cerebral inflammation but it is unknown how a concomitant bone …
associated with worsening cerebral inflammation but it is unknown how a concomitant bone …