Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …

It is estimated that 1 billion people around the world are vitamin D deficient. Vitamin D
deficiency has been linked to various inflammatory diseases. However, the mechanism by …

Inflammatory cells and mediators are an essential component of the tumor
microenvironment. Inflammatory circuits can differ considerably in different tumors in terms of …

Tumour necrosis factor (TNF) is a major inflammatory cytokine that was first identified for its
ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to …

Exercise is recognized by clinicians in the field of clinical oncology for its potential role in
reducing the risk of certain cancers and in reducing the risk of disease recurrence and …

The consequences of prostate cancer metastasis remain severe, with huge impact on the
mortality and overall quality of life of affected patients. Despite the convoluted interplay and …

Background Anti-cancer therapies lead to chronic non-resolving inflammation and reduced
immune function. One potential therapy is exercise training, but the effectiveness of these …

Tumor necrosis factor (TNF) is a multifunctional cytokine that plays important roles in diverse
cellular events such as cell survival, proliferation, differentiation, and death. As a pro …

Tumour necrosis factor alpha is a member of the TNF/TNFR cytokine superfamily. In
common with other family members, TNF-α is involved in maintenance and homeostasis of …