COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

From alpha to omicron: how different variants of concern of the SARS-Coronavirus-2 impacted the world

M Andre, LS Lau, MD Pokharel, J Ramelow, F Owens… - Biology, 2023 - mdpi.com
Simple Summary This review article comprehensively discussed the evolution of the SARS-
CoV-2 virus since its initial outbreak in 2019. Specifically, we have provided insights into the …

[HTML][HTML] Enhanced neutralization resistance of SARS-CoV-2 omicron subvariants BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2

P Qu, JP Evans, JN Faraone, YM Zheng, C Carlin… - Cell host & …, 2023 - cell.com
The continued evolution of SARS-CoV-2 has led to the emergence of several new Omicron
subvariants, including BQ. 1, BQ. 1.1, BA. 4.6, BF. 7, and BA. 2.75. 2. Here, we examine the …

Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5

I Kimura, D Yamasoba, T Tamura, N Nao, T Suzuki… - Cell, 2022 - cell.com
After the global spread of the SARS-CoV-2 Omicron BA. 2, some BA. 2 subvariants,
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …

Neutralization of the SARS-CoV-2 omicron BA. 4/5 and BA. 2.12. 1 subvariants

P Qu, J Faraone, JP Evans, X Zou… - … England Journal of …, 2022 - Mass Medical Soc
Omicron Neutralization after Covid-19 Vaccination After two doses of mRNA vaccine, health
care workers had less viral neutralizing-antibody activity against the BA. 4/5 and BA. 2.12. 1 …

Enhanced evasion of neutralizing antibody response by Omicron XBB. 1.5, CH. 1.1, and CA. 3.1 variants

P Qu, JN Faraone, JP Evans, YM Zheng, C Carlin… - Cell reports, 2023 - cell.com
Omicron subvariants continuingly challenge current vaccination strategies. Here, we
demonstrate nearly complete escape of the XBB. 1.5, CH. 1.1, and CA. 3.1 variants from …

[HTML][HTML] Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

P Qu, K Xu, JN Faraone, N Goodarzi, YM Zheng… - Cell, 2024 - cell.com
Evolution of SARS-CoV-2 requires the reassessment of current vaccine measures. Here, we
characterized BA. 2.86 and XBB-derived variant FLip by investigating their neutralization …

Evasion of neutralizing antibody responses by the SARS-CoV-2 BA. 2.75 variant

P Qu, JP Evans, YM Zheng, C Carlin, LJ Saif, EM Oltz… - Cell host & …, 2022 - cell.com
Summary The newly emerged BA. 2.75 severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant contains 9 additional mutations in its spike (S) protein compared to …

Neutralization escape, infectivity, and membrane fusion of JN. 1-derived SARS-CoV-2 SLip, FLiRT, and KP. 2 variants

P Li, JN Faraone, CC Hsu, M Chamblee, YM Zheng… - Cell reports, 2024 - cell.com
We investigate JN. 1-derived subvariants SLip, FLiRT, and KP. 2 for neutralization by
antibodies in vaccinated individuals, severe acute respiratory syndrome coronavirus 2 …

Immune evasion and membrane fusion of SARS-CoV-2 XBB subvariants EG. 5.1 and XBB. 2.3

JN Faraone, P Qu, N Goodarzi, YM Zheng… - Emerging Microbes & …, 2023 - Taylor & Francis
Immune evasion by SARS-CoV-2 paired with immune imprinting from monovalent mRNA
vaccines has resulted in attenuated neutralizing antibody responses against Omicron …