Polymeric prosthetic heart valves: A review of current technologies and future directions

SK Singh, M Kachel, E Castillero, Y Xue… - Frontiers in …, 2023 - frontiersin.org
Valvular heart disease is an important source of cardiovascular morbidity and mortality.
Current prosthetic valve replacement options, such as bioprosthetic and mechanical heart …

Pediatric pulmonary valve replacements: Clinical challenges and emerging technologies

M Crago, DS Winlaw, S Farajikhah… - Bioengineering & …, 2023 - Wiley Online Library
Congenital heart diseases (CHDs) frequently impact the right ventricular outflow tract,
resulting in a significant incidence of pulmonary valve replacement in the pediatric …

Age-related enhanced degeneration of bioprosthetic valves due to leaflet calcification, tissue crosslinking, and structural changes

Y Xue, AP Kossar, A Abramov, A Frasca… - Cardiovascular …, 2023 - academic.oup.com
Abstract Aims Bioprosthetic heart valves (BHVs), made from glutaraldehyde-fixed heterograft
materials, are subject to more rapid structural valve degeneration (SVD) in paediatric and …

Double‐network hydrogel armored decellularized porcine pericardium as durable bioprosthetic heart valves

S Cheng, X Liu, Y Qian, M Maitusong… - Advanced …, 2022 - Wiley Online Library
Heart valves have extraordinary fatigue resistance which beat≈ 3 billion times in a lifetime.
Bioprosthetic heart valves (BHVs) made from fixed heteroplasm that are incrementally used …

[HTML][HTML] Hybrid heart valves with VEGF-loaded zwitterionic hydrogel coating for improved anti-calcification and re-endothelialization

Q Tong, A Sun, Z Wang, T Li, X He, Y Qian, Z Qian - Materials Today Bio, 2022 - Elsevier
With the aging of the population in worldwide, valvular heart disease has become one of the
most prominent life-threatening diseases in human health, and heart valve replacement …

Prosthetic heart valves for transcatheter aortic valve replacement

X Hu, S Li, P Peng, B Wang, W Liu, X Dong, X Yang… - …, 2023 - Wiley Online Library
Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster
postoperative recovery, which has brought the possibility to the elderly patient with valvular …

Recent Advances in the Modification and Improvement of Bioprosthetic Heart Valves

Q Tong, J Cai, Z Wang, Y Sun, X Liang, Q Xu… - Small, 2024 - Wiley Online Library
Valvular heart disease (VHD) has become a burden and a growing public health problem in
humans, causing significant morbidity and mortality worldwide. An increasing number of …

[HTML][HTML] Effects of membrane and flexural stiffnesses on aortic valve dynamics: identifying the mechanics of leaflet flutter in thinner biological tissues

EL Johnson, MR Rajanna, CH Yang, MC Hsu - Forces in mechanics, 2022 - Elsevier
Valvular pathologies that induce deterioration in the aortic valve are a common cause of
heart disease among aging populations. Although there are numerous available …

[HTML][HTML] Who Lives Longer, the Valve or the Patient? The Dilemma of TAVI Durability and How to Optimize Patient Outcomes

V Cesario, O Oliva, C De Biase, A Beneduce… - Journal of Clinical …, 2024 - mdpi.com
Over the past few years, transcatheter aortic valve implantation (TAVI) imposed itself as the
first-choice therapy for symptomatic aortic stenosis (AS) in elderly patients at surgical risk …

Poly-2-methyl-2-oxazoline–modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration

A Zakharchenko, Y Xue, S Keeney… - Proceedings of the …, 2022 - National Acad Sciences
Bioprosthetic heart valves (BHV) fabricated from glutaraldehyde-fixed heterograft tissue,
such as bovine pericardium (BP), are widely used for treating heart valve disease, a group of …