In recent years, there have been significant advancements in our understanding of acute
kidney injury (AKI) and its impact on outcomes across medicine. Research based on single …

Growth and development are two major aspects of children not readily apparent in adults.
Clearance in the paediatric population should be investigated using models that describe …

Clinical biochemists have long known the analytical and clinical limitations of creatinine and
creatinine clearance measurement in the assessment of glomerular filtration rate (GFR). This …

Neonates who are critically ill are at high risk for acute kidney injury (AKI) as the result of
several potential exposures (eg, nephrotoxic medications, sepsis, hypotension, adverse …

Neonates, infants, and children differ from adults in many aspects, not just in age, weight,
and body composition. Growth, maturation and environmental factors affect drug kinetics …

BACKGROUND: This is a retrospective study on a large hospital database to establish age-
and sex-related mean values and reference ranges for serum creatinine (Scr), obtained with …

Since few data are available about factors affecting renal maturation especially in the lower
gestational ages (GA), the aim of this work was to study postnatal renal function in a …

The aim of this study was to determine the incidence, risk factors, and outcome of acute
kidney injury (AKI) in extremely low birth weight (ELBW) infants. In a case–control study …

The renal system plays a tremendous role in growth and development of infants and
children. The kidney itself also undergoes a maturation process as it transitions from the fetal …

Objective To determine the incidence of acute kidney injury (AKI) in infants exposed to
nephrotoxic drug combinations admitted to 268 neonatal intensive care units managed by …