A direct role for small non-coding RNAs in DNA damage response
FA di Fagagna - Trends in cell biology, 2014 - cell.com
Historically, the role of cellular RNA has been subordinate and ancillary to DNA. Protein-
coding mRNA conveys the information content of DNA, and transfer RNAs and ribosomal …
coding mRNA conveys the information content of DNA, and transfer RNAs and ribosomal …
MicroRNA-21 gene and cancer
Y Huang, YB Yang, XH Zhang, XL Yu, ZB Wang… - Medical oncology, 2013 - Springer
MicroRNAs (miRNAs) are a class of 18–27-nucleotides single-stranded RNA molecules that
regulate gene expression at the post-transcriptional level. It has been demonstrated that …
regulate gene expression at the post-transcriptional level. It has been demonstrated that …
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
M Teta, YS Choi, T Okegbe, G Wong, OH Tam… - …, 2012 - journals.biologists.com
MicroRNAs (miRNAs) regulate the expression of many mammalian genes and play key
roles in embryonic hair follicle development; however, little is known of their functions in …
roles in embryonic hair follicle development; however, little is known of their functions in …
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity
F Bollmann, J Art, J Henke, K Schrick… - Nucleic acids …, 2014 - academic.oup.com
Resveratrol shows beneficial effects in inflammation-based diseases like cancer,
cardiovascular and chronic inflammatory diseases. Therefore, the molecular mechanisms of …
cardiovascular and chronic inflammatory diseases. Therefore, the molecular mechanisms of …
Functional and molecular insights into KSRP function in mRNA decay
P Briata, CY Chen, A Ramos, R Gherzi - Biochimica et Biophysica Acta …, 2013 - Elsevier
KSRP is a single strand nucleic acid binding protein that controls gene expression at
multiple levels. In this review we focus on the recent molecular, cellular, and structural …
multiple levels. In this review we focus on the recent molecular, cellular, and structural …
MicroRNAs, DNA damage response and ageing
Ageing is a multifactorial and integrated gradual deterioration affecting the most of biological
process of cells. MiRNAs are differentially expressed in the cellular senescence and play …
process of cells. MiRNAs are differentially expressed in the cellular senescence and play …
Therapeutic potential of the miRNA–ATM axis in the management of tumor radioresistance
The ataxia-telangiectasia mutated (ATM) protein kinase is widely known for its function as a
chief mobilizer of the DNA damage response (DDR) upon DNA double-strand breaks. ATM …
chief mobilizer of the DNA damage response (DDR) upon DNA double-strand breaks. ATM …
Post-translational modifications and RNA-binding proteins
RNA-binding proteins affect cellular metabolic programs through development and in
response to cellular stimuli. Though much work has been done to elucidate the roles of a …
response to cellular stimuli. Though much work has been done to elucidate the roles of a …
K-homology splicing regulatory protein (KSRP) promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer
RK Bikkavilli, SA Zerayesus, M Van Scoyk… - Journal of Biological …, 2017 - ASBMB
AU-rich element-binding proteins (ARE-BPs) offer post-transcriptional regulation of gene
expression via physical interaction and recruitment of RNA decay machinery to the AU-rich …
expression via physical interaction and recruitment of RNA decay machinery to the AU-rich …
[图书][B] The role of microRNAs in the cellular response to ionizing radiations
N Joly-Tonetti, J Lamartine - 2012 - Citeseer
Ionising irradiation is a major issue in our society. Although public attention mainly focuses
on it when industrial disasters or medical accidents occur, or in military contexts, it is also a …
on it when industrial disasters or medical accidents occur, or in military contexts, it is also a …