Introduction: Ten years ago, we put forward the metabolo-oncogenic nature of fatty acid
synthase (FASN) in breast cancer. Since the conception of this hypothesis, which provided a …

Fatty acid synthase (FASN) is a key enzyme involved in neoplastic lipogenesis.
Overexpression of FASN is common in many cancers, and accumulating evidence suggests …

Tumour growth and dissemination is largely dependent on nutrient availability. It has
recently emerged that the tumour microenvironment is rich in a diverse array of lipids that …

The present review provides an up-to-date summary of the findings on the lipid-lowering
effects of the most important nutraceuticals and functional foods. Based on current …

Lipids constitute some of nature's most abundant molecules, being found in virtually all
forms of life. They are derived by condensation reactions involving acetate units and may be …

Tannins, polyphenols in medicinal plants, have been divided into two groups of
hydrolysable and condensed tannins, including gallotannins, ellagitannins, and (–) …

Hyperlipidemia is one of the major risk factor for the development of cardiovascular disease.
Hypolipidemic nutraceuticals and functional foods help improve serum lipid profiles as …

Mitochondria are emerging as idealized targets for anti-cancer drugs. One reason for this is
that although these organelles are inherent to all cells, drugs are being developed that …

Abstract Introduction Inhibiting the enzyme Fatty Acid Synthase (FASN) leads to apoptosis of
breast carcinoma cells, and this is linked to human epidermal growth factor receptor 2 …

Background Fatty acid synthase (FASN) is overexpressed and hyperactivated in several
human carcinomas, including lung cancer. We characterize and compare the anti-cancer …