[HTML][HTML] Delivery strategies of amphotericin B for invasive fungal infections

X Wang, IS Mohammad, L Fan, Z Zhao… - … Pharmaceutica Sinica B, 2021 - Elsevier
Invasive fungal infections (IFIs) represent a growing public concern for clinicians to manage
in many medical settings, with substantial associated morbidities and mortalities. Among …

Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight

H Jamshaid, FU Din, GM Khan - Journal of Nanobiotechnology, 2021 - Springer
As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …

[HTML][HTML] Bougainvillea flower extract mediated zinc oxide's nanomaterials for antimicrobial and anticancer activity

MA Rauf, M Oves, FU Rehman, AR Khan… - Biomedicine & …, 2019 - Elsevier
The zinc oxide nanomaterials (ZnO-NMs), owing to their broad biomedical applications have
lately attracted the incredible interest in the development of therapeutic agents against …

Activity of amphotericin B-loaded chitosan nanoparticles against experimental cutaneous leishmaniasis

A Riezk, K Van Bocxlaer, V Yardley, S Murdan, SL Croft - Molecules, 2020 - mdpi.com
Chitosan nanoparticles have gained attention as drug delivery systems (DDS) in the medical
field as they are both biodegradable and biocompatible with reported antimicrobial and anti …

Potent antifungal agents and use of nanocarriers to improve delivery to the infected site: A systematic review

S Nagaraj, S Manivannan… - Journal of Basic …, 2021 - Wiley Online Library
There are four major classes of antifungals with the predominant mechanism of action being
targeting of cell wall or cell membrane. As in other drugs, low solubility of these compounds …

Key design features of lipid nanoparticles and electrostatic charge-based lipid nanoparticle targeting

V Gyanani, R Goswami - Pharmaceutics, 2023 - mdpi.com
Lipid nanoparticles (LNP) have gained much attention after the approval of mRNA COVID-
19 vaccines. The considerable number of currently ongoing clinical studies are testament to …

In-silico approach as a tool for selection of excipients for safer amphotericin B nanoformulations

PA Todke, PV Devarajan - Journal of Controlled Release, 2022 - Elsevier
Safer and efficacious Amphotericin B (AmB) nanoformulations can be designed by
augmenting AmB in the monomeric or super-aggregated state, and restricting the …

Thiohydantoins as anti-leishmanial agents: n vitro biological evaluation and multi-target investigation by molecular docking studies

PG Camargo, BTS Bortoleti, M Fabris… - Journal of …, 2022 - Taylor & Francis
Leishmaniasis is a neglected tropical disease caused by protozoa of the genus Leishmania.
The first-line treatment of this disease is still based on pentavalent antimonial drugs that …

Novel chloroquine loaded curcumin based anionic linear globular dendrimer G2: A metabolomics study on Plasmodium falciparum in vitro using 1H NMR …

T Elmi, MS Ardestani, F Hajialiani, M Motevalian… - Parasitology, 2020 - cambridge.org
Due to side-effects and inefficiency of the drugs used in malaria treatment, finding alternative
medicine with less side-effects has attracted much attention. In this regard, in the present …

Coalition of biological agent (melatonin) with chemotherapeutic agent (amphotericin B) for combating visceral leishmaniasis via oral administration of modified solid …

S Parvez, G Yadagiri, K Arora, A Javaid… - ACS Biomaterials …, 2021 - ACS Publications
In this study, 2-hydroxypropyl-β-cyclodextrin (HPβCD) grafted solid lipid nanoparticle (SLN)-
based bioconjugate was synthesized and used for administering a combination of melatonin …