Planarians (Platyhelminthes)—An emerging model organism for investigating innate immune mechanisms

LJ Kangale, D Raoult, PE Fournier… - Frontiers in Cellular …, 2021 - frontiersin.org
An organism responds to the invading pathogens such as bacteria, viruses, protozoans, and
fungi by engaging innate and adaptive immune system, which functions by activating …

The Wnt/Ca2+ signaling pathway is essential for the regeneration of GABAergic neurons in planarian Dugesia japonica

H Zhen, H Deng, Q Song, M Zheng, Z Yuan… - The FASEB …, 2020 - Wiley Online Library
The growth and differentiation of neurons are critical events in the establishment of proper
neuron connectivity and function. Planarians have a remarkable ability to completely …

The planarian Schmidtea mediterranea is a new model to study host-pathogen interactions during fungal infections

EI Maciel, C Jiang, PG Barghouth, CJ Nobile… - Developmental & …, 2019 - Elsevier
Candida albicans is one of the most common fungal pathogens of humans. Currently, there
are limitations in the evaluation of C. albicans infection in existing animal models, especially …

14-3-3ζ and 14-3-3ε are involved in innate immune responses in Pacific abalone (Haliotis discus hannai)

R Xue, D Yang, Y Han, Q Deng, X Wang, X Liu… - Developmental & …, 2021 - Elsevier
Abstract The 14-3-3 proteins play important roles in various cellular processes by binding to
different ligands, but little is known about these proteins in mollusks. In this study, two 14-3-3 …

DjFARP Contributes to the Regeneration and Maintenance of the Brain through Activation of DjRac1 in Dugesia japonica

Q Song, H Geng, H Zhen, H Liu, H Deng, Z Yuan… - Molecular …, 2023 - Springer
FERM, RhoGEF, and Pleckstrin domain protein (FARP) mediated RhoGTPase pathways are
involved in diverse biological processes, such as neuronal development and tumorigenesis …

Transcriptomic responses of the clam Meretrix meretrix to the organophosphorus pesticide (dimethoate)

J Cao, B Wang, X Tan - Ecotoxicology, 2019 - Springer
Organophosphorus pesticides (OPs) play a certain role in promoting the development of
agriculture and forestry, but they may cause potential harm to aquatic life when entering …

Comparative and evolutionary analysis of the 14-3-3 family genes in eleven fishes

J Cao, X Tan - Gene, 2018 - Elsevier
3-3 proteins are a type of highly conserved acidic proteins, which are distributed over a wide
variety of organisms and are involved in multiple cellular processes. While the comparative …

14-3-3 gene family in spotted sea bass (Lateolabrax maculatus): Genome-wide identification, phylogenetic analysis and expression profiles after salinity stress

K Zhang, H Wen, J Li, X Qi, H Fan, X Zhang… - … and Physiology Part A …, 2019 - Elsevier
Abstract The tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation (14-3-3)
proteins are a group of highly conserved homologous and heterologous proteins involved in …

Platyhelminthes: molecular dissection of the planarian innate immune system

EI Maciel, NJ Oviedo - Advances in Comparative Immunology, 2018 - Springer
Multicellular organisms rely on their immune system to fight pathogens, maintain
homeostasis, and repair tissues. Different environments and evolutionary paths have …

Innate and intrinsic immunity in planarians

L Gao, A Li, N Li, X Liu, H Deng, B Zhao… - Invertebrate Survival …, 2017 - isj.unimore.it
Abstract Planarians in the Phylum Platyhelminthes occupy a peculiar phylogenetic position
and have a strong regenerative capacity of their adult tissues, which has aroused general …