[HTML][HTML] Fenugreek and its effects on muscle performance: a systematic review

WI Albaker - Journal of Personalized Medicine, 2023 - mdpi.com
Fenugreek extracts possess promising physiological and pharmacological properties in
human and animal models. This review aims to provide a scientific and comprehensive …

[HTML][HTML] The role of fenugreek in the management of type 2 diabetes

M Haxhiraj, K White, C Terry - International journal of molecular sciences, 2024 - mdpi.com
The number of people diagnosed with type 2 diabetes is on the increase worldwide. Of
growing concern, the prevalence of type 2 diabetes in children and youths is increasing …

[HTML][HTML] Trigonelline prevents kidney stone formation processes by inhibiting calcium oxalate crystallization, growth and crystal-cell adhesion, and downregulating …

P Peerapen, W Boonmark, V Thongboonkerd - Biomedicine & …, 2022 - Elsevier
Trigonelline is the second most abundant bioactive alkaloid found in coffee. It is classified as
a phytoestrogen with similar structure as of estradiol and exhibits an estrogenic effect. A …

[HTML][HTML] Methoxyisoflavan derivative from Trigonella stellata inhibited quorum sensing and virulence factors of Pseudomonas aeruginosa

NG Naga, AA Zaki, DE El-Badan, HS Rateb… - World Journal of …, 2022 - Springer
The number of deaths caused by multidrug-resistant Pseudomonas aeruginosa has risen in
the recent decade. The development of quorum sensing inhibition (QSI) is a promising …

[HTML][HTML] Pharmacological Activities, Therapeutic Effects, and Mechanistic Actions of Trigonelline

V Nguyen, EG Taine, D Meng, T Cui, W Tan - International Journal of …, 2024 - mdpi.com
Trigonelline (TRG) is a natural polar hydrophilic alkaloid that is found in many plants such as
green coffee beans and fenugreek seeds. TRG potentially acts on multiple molecular …

Trigonelline induces autophagy to protect mesangial cells in response to high glucose via activating the miR-5189-5p-AMPK pathway

C Chen, J Ma, CS Miao, H Zhang, M Zhang, X Cao… - Phytomedicine, 2021 - Elsevier
Background Diabetic nephropathy (DN) is a primary cause of end‐stage renal disease.
Increasing evidence indicates that microRNAs (miRNAs) are involved in DN pathogenesis …

[HTML][HTML] Biomolecule from Trigonella stellata from Saudi Flora to Suppress Osteoporosis via Osteostromal Regulations

HIM Ibrahim, HM Darrag, MR Alhajhoj, HE Khalil - Plants, 2020 - mdpi.com
Trigonella stellata has used in folk medicine as palatable and nutraceutical herb. It also
regulates hypocholesterolemia, hypoglycemia, and has showed anti-inflammatory activities …

[HTML][HTML] Characterization of Possible α-Glucosidase Inhibitors from Trigonella stellata Extract Using LC–MS and In Silico Molecular Docking

A Elwekeel, D El Amir, EIA Mohamed, E Amin… - Plants, 2022 - mdpi.com
The current study accentuates the significance of performing the multiplex approach of LC-
HRESIMS, biological activity, and docking studies in drug discovery, taking into …

Pterostilbene as a phytochemical compound induces signaling pathways involved in the apoptosis and death of mutant P53-breast cancer cell lines

AM Elsherbini, SA Sheweita, AS Sultan - Nutrition and Cancer, 2021 - Taylor & Francis
Pterostilbene is a natural nonflavonoid polyphenolic compound. It shows a remarkable
range of biological activities, including antiproliferative, antiinflammatory, and antioxidant …

[HTML][HTML] Validation of the traditional medicinal use of a Mexican endemic orchid (Prosthechea karwinskii) through UPLC-ESI-qTOF-MS/MS characterization of its …

GS Barragán-Zarate, L Lagunez-Rivera, R Solano… - Heliyon, 2022 - cell.com
Abstract Ethnopharmacological relevance The orchid Prosthechea karwinskii is a medicinal
orchid in Oaxaca, Mexico, used to treat diabetes, cough, wounds, and burns, prevent …