While efficient glucose transport is essential for all cells, in the case of the human placenta,
glucose transport requirements are two-fold; provision of glucose for the growing fetus in …

The facilitated diffusion of glucose, galactose, fructose, urate, myoinositol, and
dehydroascorbic acid in mammals is catalyzed by a family of 14 monosaccharide transport …

Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to
hypertrophy and matrix expansion, eventually culminating in progressive kidney failure …

Glucose is a basic nutrient in most of the creatures; its transport through biological
membranes is an absolute requirement of life. This role is fulfilled by glucose transporters …

Highly proliferative cells, including cancer cells, require a constant supply of molecular
building blocks to support their growth. To acquire substrates such as glucose and amino …

GLUT8 is a class III sugar transporter predominantly expressed in testis and brain. In
contrast to the class I and class II transporters, hydrophobicity plots predict a short …

This review examines the development of structure and function of the human GLUT
proteins, gene family hSLC2A. These proteins are essential for moving the key metabolites …

ABSTRACT Aims/Introduction The aim of the present study was to evaluate the placental
expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in term …

Objective In utero exposure to valproic acid (VPA) has been associated with worse
pregnancy outcomes compared to all other antiepileptic drugs. We have previously shown …

Background In general, sugar porters function by proton-coupled symport or facilitative
transport modes. Symporters, coupled to electrochemical energy, transport nutrients against …