As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Glaucoma, a leading cause of blindness in the world, can be challenging to diagnose
because symptoms often appear at late stage of the disease, and challenging to treat …

In the mammalian primary visual cortex, neural tuning to stimulus orientation is organized in
either columnar or salt-and-pepper patterns across species. For decades, this sharp contrast …

Primary visual cortices in many mammalian species exhibit modular and periodic orientation
preference maps arranged in pinwheel-like layouts. The role of inherited traits as opposed to …

Tree shrews are small mammals with excellent vision and are closely related to primates.
They have been used extensively as a model for studying refractive development, myopia …

Myopia and glaucoma are both increasing in prevalence and are linked by an unknown
mechanism as many epidemiologic studies have identified moderate to high myopia as an …

Glaucoma is a group of eye diseases afflicting more than 70 million people worldwide. It is
characterized by damage to retinal ganglion cells (RGCs) that ultimately leads to the death …

Purpose: Glaucoma remains a leading cause of irreversible blindness worldwide. Animal
glaucoma models replicate high intraocular pressure, a risk factor for glaucoma, to induce …

The tree shrew (Tupaia belangeri) has long been proposed as a suitable alternative to non-
human primates (NHPs) in biomedical and laboratory research due to its close evolutionary …