The Principle of Cortical Development and Evolution

Z Yang - Neuroscience bulletin, 2024 - Springer
Human's robust cognitive abilities, including creativity and language, are made possible, at
least in large part, by evolutionary changes made to the cerebral cortex. This paper reviews …

Advancements in Genetic Marker Exploration for Livestock Vertebral Traits with a Focus on China

MZ Khan, W Chen, B Huang, X Liu, X Wang, Y Liu… - Animals, 2024 - mdpi.com
Simple Summary In the context of increasing global meat consumption, the meat production
industry is facing significant challenges as it strives to enhance attributes related to livestock …

ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period

M Sun, Y Gao, Z Li, L Yang, G Liu… - Proceedings of the …, 2024 - National Acad Sciences
The molecular basis for cortical expansion during evolution remains largely unknown. Here,
we report that fibroblast growth factor (FGF)-extracellular signal-regulated kinase (ERK) …

Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development

Y Liu, X Luo, Y Sun, K Chen, T Hu, B You, J Xu… - Developmental Cell, 2024 - cell.com
Understanding the cellular and genetic mechanisms driving human-specific features of
cortical development remains a challenge. We generated a cell-type resolved atlas of …

Excitatory neurons and oligodendrocyte precursor cells are vulnerable to focal cortical dysplasia type IIIa as suggested by single‐nucleus multiomics

Y Liu, Y Li, Y Zhang, Y Fang, L Lei, J Yu… - Clinical and …, 2024 - Wiley Online Library
Background Focal cortical dysplasia (FCD) is a heterogeneous group of cortical
developmental malformations that constitute a common cause of medically intractable …

[HTML][HTML] The SoxE factor Sox9 is selectively expressed in indirect pathway striatal projection neurons and regulates synaptogenesis

X Song, X Li, X Pan, H Yang, K Wang, T Yang… - Fundamental …, 2024 - Elsevier
Striatum, as the largest structure of the basal ganglia, serves as a center for information
transmission and is critical for motor function and reward perception. However, the genetic …

Lateral/caudal ganglionic eminence makes limited contribution to cortical oligodendrocytes

J Li, F Yang, Y Tian, Z Wang, D Qi, Z Yang, J Song… - Elife, 2024 - elifesciences.org
The emergence of myelinating oligodendrocytes represents a pivotal developmental
milestone in vertebrates, given their capacity to ensheath axons and facilitate the swift …

Mouse Cortical Cellular Diversification Through Lineage Progression of Radial Glia

X LI, L Yang, Y Gao, Z Wang, Z Li, G Liu, Z Xu, Z Zhang… - bioRxiv, 2025 - biorxiv.org
Cortical radial glia (RGs) sequentially generate pyramidal neurons (PyNs) and glia. In this
study, we investigated the molecular logic underlying cortical cellular diversification using …

ERK signaling drives evolutionary expansion of the mammalian cerebral cortex

M Sun, Y Gao, Z Li, L Yang, G Liu, Z Xu, R Guo, Y You… - bioRxiv, 2023 - biorxiv.org
The molecular basis for cortical expansion during evolution remains largely unknown. Here,
we found that FGF-extracellular signal-regulated kinase (ERK) signaling promotes the self …