Protein SUMOylation modification and its associations with disease
Y Yang, Y He, X Wang, Z Liang, G He… - Open …, 2017 - royalsocietypublishing.org
SUMOylation, as a post-translational modification, plays essential roles in various biological
functions including cell growth, migration, cellular responses to stress and tumorigenesis …
functions including cell growth, migration, cellular responses to stress and tumorigenesis …
Mapping protein post-translational modifications with mass spectrometry
ES Witze, WM Old, KA Resing, NG Ahn - Nature methods, 2007 - nature.com
Post-translational modifications of proteins control many biological processes, and
examining their diversity is critical for understanding mechanisms of cell regulation. Mass …
examining their diversity is critical for understanding mechanisms of cell regulation. Mass …
GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs
Small ubiquitin-like modifiers (SUMOs) regulate a variety of cellular processes through two
distinct mechanisms, including covalent sumoylation and non-covalent SUMO interaction …
distinct mechanisms, including covalent sumoylation and non-covalent SUMO interaction …
[PDF][PDF] Sumoylation promotes the stability of the DNA sensor cGAS and the adaptor STING to regulate the kinetics of response to DNA virus
During viral infection, sensing of cytosolic DNA by the cyclic GMP-AMP synthase (cGAS)
activates the adaptor protein STING and triggers an antiviral response. Little is known about …
activates the adaptor protein STING and triggers an antiviral response. Little is known about …
System-wide changes to SUMO modifications in response to heat shock
Covalent conjugation of the small ubiquitin-like modifier (SUMO) proteins to target proteins
regulates many important eukaryotic cellular mechanisms. Although the molecular …
regulates many important eukaryotic cellular mechanisms. Although the molecular …
The many functions of APE1/Ref-1: not only a DNA repair enzyme
G Tell, F Quadrifoglio, C Tiribelli… - Antioxidants & redox …, 2009 - liebertpub.com
Abstract APE1/Ref-1 (APE1), the mammalian ortholog of Escherichia coli Xth, and a
multifunctional protein possessing both DNA repair and transcriptional regulatory activities …
multifunctional protein possessing both DNA repair and transcriptional regulatory activities …
pSumo-CD: predicting sumoylation sites in proteins with covariance discriminant algorithm by incorporating sequence-coupled effects into general PseAAC
Motivation: Sumoylation is a post-translational modification (PTM) process, in which small
ubiquitin-related modifier (SUMO) is attaching by covalent bonds to substrate protein. It is …
ubiquitin-related modifier (SUMO) is attaching by covalent bonds to substrate protein. It is …
Systematic study of protein sumoylation: Development of a site‐specific predictor of SUMOsp 2.0
Protein sumoylation is an important reversible post‐translational modification on proteins,
and orchestrates a variety of cellular processes. Recently, computational prediction of …
and orchestrates a variety of cellular processes. Recently, computational prediction of …
Large-scale comparative assessment of computational predictors for lysine post-translational modification sites
Lysine post-translational modifications (PTMs) play a crucial role in regulating diverse
functions and biological processes of proteins. However, because of the large volumes of …
functions and biological processes of proteins. However, because of the large volumes of …
Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery
TH Chang, T Kubota, M Matsuoka, S Jones… - PLoS …, 2009 - journals.plos.org
Ebola Zaire virus is highly pathogenic for humans, with case fatality rates approaching 90%
in large outbreaks in Africa. The virus replicates in macrophages and dendritic cells (DCs) …
in large outbreaks in Africa. The virus replicates in macrophages and dendritic cells (DCs) …