Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks,
including dissolving the components and facilitating chemical reactions, because many …

The reactions of organic azides and alkynes catalysed by copper species represent the
prototypical examples of click chemistry. The so-called CuAAC reaction (copper-catalysed …

The use of water as solvent features many benefits such as improving reactivities and
selectivities, simplifying the workup procedures, enabling the recycling of the catalyst and …

Water is the solvent used by nature for biological chemistry. Considering the enormous
variety of biological organic synthetic pathways and the complicated molecular structures …

The emergence of bioorthogonal reactions has greatly broadened the scope of biomolecule
labeling and detecting. Of all the bioorthogonal reactions that have been developed, the …

The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly
applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the …

Tris (heterocyclemethyl) amines containing mixtures of 1, 2, 3-triazolyl, 2-benzimidazoyl, and
2-pyridyl components were prepared for ligand acceleration of the copper-catalyzed azide …

Even though the existence of 1, 2, 3‐triazoles has been known for more than a century, the
recent discovery of a copper (I) catalyzed version of this reaction has attributed …

Mixed self-assembly of ligands 1, 2, 1, 6-hexanediamine (HDA), and Pd (NO3) 2 afforded
Fujita-type metal organic polyhedron MOP1 (diameter≈ 8.2 nm), which is covalently …

Within the green chemistry context, heterogeneous catalysis applied to organic synthesis is
becoming an increasingly important field, bringing its own innovation and specific properties …