Neonatal diabetes mellitus (NDM) is noted as a genetic, heterogeneous, and rare disease in
infants. NDM occurs due to a single-gene mutation in neonates. A common source for …

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia as a
result of progressive loss of pancreatic β cells, which could lead to several debilitating …

Introduction Monogenic diabetes, a form of diabetes mellitus, is caused by a mutation in a
single gene and may account for 1–2% of all clinical forms of diabetes. To date, more than …

Aims HNF1B syndrome is caused by defects in the hepatocyte nuclear factor 1B (HNF1B)
gene, which leads to maturity‐onset diabetes of the young type 5 and congenital organ …

Neonatal diabetes mellitus (NDM) is a rare, insulin-dependent diabetes that manifests within
the first month of life and requires insulin therapy for management. NDM is categorized into …

Current global estimates suggest that more than 537 million young adults are living with
diabetes worldwide, which has become a serious health burden. From the genetic …

Context Biallelic mutations in the PTF1A enhancer are the commonest cause of isolated
pancreatic agenesis. These patients do not have severe neurological features associated …

Aims Neonatal diabetes mellitus (NDM) is a rare disease where diabetes presents during
the first six months of life. There are two types of this disorder: permanent neonatal diabetes …

Neonatal diabetes mellitus is a rare disorder of glucose metabolism with onset within the first
6 months of life. The initial treatment is based on insulin infusion. The technologies for …

Context In the last decade the Sanger method of DNA sequencing has been replaced by
next-generation sequencing (NGS). NGS is valuable in conditions characterized by high …