Recent advances in small molecular near-infrared fluorescence probes for a targeted diagnosis of the Alzheimer disease

Y Liu, D Zhuang, J Wang, H Huang, R Li, C Wu… - Analyst, 2022 - pubs.rsc.org
Nowadays, it is still quite challenging to achieve an early diagnosis of the Alzheimer disease
(AD) in clinics. The burgeoning near-infrared fluorescence (NIRF) imaging fulfills the …

Low molecular weight self-assembling peptide-based materials for cell culture, antimicrobial, anti-inflammatory, wound healing, anticancer, drug delivery, bioimaging …

AK Das, PK Gavel - Soft Matter, 2020 - pubs.rsc.org
In this review, we have focused on the design and development of low molecular weight self-
assembling peptide-based materials for various applications including cell proliferation …

Synthetic nanoassemblies for regulating organelles: from molecular design to precision therapeutics

Y Guo, P Li, X Guo, C Yao, D Yang - ACS nano, 2024 - ACS Publications
Each organelle referring to a complex multiorder architecture executes respective biological
processes via its distinct spatial organization and internal microenvironment. As the …

Multifunction in one molecule: mitochondrial imaging and photothermal & photodynamic cytotoxicity of fast-response near-infrared fluorescent probes with aggregation …

L Zhang, JL Wang, XX Ba, SY Hua… - … Applied Materials & …, 2021 - ACS Publications
HJS and DHJS, two near-infrared emissive and mitochondria-targeted therapy probes, have
been designed. They exhibited photothermal & photodynamic cytotoxicity and aggregation …

Peptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche

Y Zhou, P Ke, X Bao, H Wu, Y Xia, Z Zhang… - Nature …, 2022 - nature.com
There is evidence to suggest that the primary tumor induces the formation of a pre-metastatic
niche in distal organs by stimulating the production of pro-metastatic factors. Given the …

Glutathione-Conjugated Fluorometric Ratiometric NIR-Silicon Nanoparticles and Its Applications for In Vitro and In Vivo Imaging

Y Iradukunda, JY Kang, X Zhao, XK Fu… - ACS Applied Bio …, 2024 - ACS Publications
Glutathione (GSH), a tripeptide molecule, is the most abundant nonprotein biothiol in living
cells, playing a crucial role in preventing oxidative damage to cellular components and …

[HTML][HTML] Self-assembly inside cellular organelles: Aspects of functions and various strategies for cancer therapy

S Kim, H Choi, S Jin, S Son, Y Lee, K Kim, JH Ryu - Giant, 2023 - Elsevier
Self-assembly generates three-dimensional architectures through the non-covalent
interactions of building blocks of various sizes, ranging from nanometers to micrometers …

Successive detection of zinc ion and citrate using a Schiff base chemosensor for enhanced prostate cancer diagnosis in biosystems

S Muthusamy, D Zhu, K Rajalakshmi… - ACS Applied Bio …, 2021 - ACS Publications
Sensitive and quantitative detection of prostate cancer (PC) requires a chemosensor with an
applicable sensing strategy. A star-shaped Schiff base triaminoguanidine-integrated …

Mitochondria-targeted self-assembly of peptide-based nanomaterials

Z Luo, Y Gao, Z Duan, Y Yi, H Wang - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Mitochondria are well known to serve as the powerhouse for cells and also the initiator for
some vital signaling pathways. A variety of diseases are discovered to be associated with …

Live-cell mitochondrial targeted NIR fluorescent covalent labeling of specific proteins using a dual localization effect

PC Saha, RS Das, S Das, N Sepay… - Bioconjugate …, 2023 - ACS Publications
Here, our designed water-soluble NIR fluorescent unsymmetrical Cy-5-Mal/TPP+ consists of
a lipophilic cationic TPP+ subunit that can selectively target and accumulate in a live-cell …