Actin is a multi-functional protein that is involved in numerous cellular processes including
cytoskeleton regulation, cell migration, and cellular integrity. In these processes, actin's role …

Meiosis is a key step during germ cell differentiation, accompanied by the activation of
thousands of genes through germline-specific chromatin reorganization. The chromatin …

The Chinese soft-shelled turtle (Pelodiscus sinensis) is extensively cultured in Asia for its
nutritional and medical value. Gonadal differentiation is fantastic in turtles, whereas …

ATP-dependent chromatin-remodeling complexes epigenetically modulate transcription of
target genes to impact a variety of developmental processes. Our lab previously …

Maintenance and self-renewal of the spermatogonial stem cell (SSC) population is the
cornerstone of male fertility. Here, we have identified a key role for the nucleosome …

The chromatin remodeler Chromodomain-helicase-DNA-binding protein 4 (CHD4) is crucial
for the development of multiple organ systems. Functional mutations of CHD4 have recently …

Differences of sex development (DSDs) are a group of congenital conditions characterized
by a discrepancy between chromosomal, gonadal, and genital sex development of an …