The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

Cisplatin is a highly effective antitumor drug generally used in the treatment of solid
malignant tumors. However, cisplatin causes severe side effects such as bone marrow …

Cadmium (Cd), an environmental toxicant, is positively associated with fetal growth
restriction (FGR). However, the mechanism by which gestational exposure to Cd induces …

Nuclear factor erythroid 2-related factor 2 (Nrf2) serves as the master regulator of antioxidant
signaling and inhibition or hyperactivation of Nrf2 pathway will result in the redox imbalance …

Facilitated transport is necessitated for large size, charged, and/or hydrophilic drugs to move
across the membrane. The drug transporters in the solute carrier (SLC) superfamily, mainly …

Chronic interstitial nephritis in agricultural communities (CINAC) is an epidemic of kidney
disease affecting specific tropical and subtropical regions worldwide and is characterized by …

Alhagi camelorum (AC) is an old plant with a significant therapeutic value throughout Africa,
Asia, and Latin America. The overuse of cisplatin (Cis> 50 mg/m2) is associated with …

The overuse of cisplatin (> 50 mg/m2) is limited to nephrotoxicity, ototoxicity, gastrotoxicity,
myelosuppression, and allergic reactions. The objective of this study was to investigate the …

Xenobiotic mediated renal toxicity is one of the major health concerns to the organisms,
including humans. New chemicals with nephrotoxic potential are continuously being added …

Phototheranostics is an emerging field in synergistic antitumor therapy in which irradiation
and sensitizers are combined to produce reactive oxygen species (ROS), bio-images, and …