Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review

J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

Current and future biomarkers for pancreatic adenocarcinoma

SH Loosen, UP Neumann, C Trautwein… - Tumor …, 2017 - journals.sagepub.com
Although pancreatic cancer is only the twelfth most common type of cancer in the world, it
features a very unfavorable prognosis. The mortality rate almost equals the incidence rate …

Diagnostic accuracy and added value of blood-based protein biomarkers for pancreatic cancer: a meta-analysis of aggregate and individual participant data

LNC Boyd, M Ali, MMG Leeflang, G Treglia… - …, 2023 - thelancet.com
Background Novel blood-based protein biomarkers may be of value for efficient, accurate,
and non-invasive diagnosis of pancreatic cancer. This study assesses the diagnostic …

Pancreatic Cancer Biomarkers: Oncogenic Mutations, Tissue and Liquid Biopsies, and Radiomics—A Review

MJ Amaral, RC Oliveira, P Donato… - Digestive diseases and …, 2023 - Springer
Pancreatic cancer is one of the most fatal malignancies, as approximately 80% of patients
are at advanced stages by the time of diagnosis. The main reason for the poor overall …

[HTML][HTML] Pancreatic ductal adenocarcinoma with a high expression of alcohol dehydrogenase 1B is associated with less aggressive features and a favorable …

K Chida, M Oshi, AM Roy, T Sato, I Endo… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Alcohol dehydrogenase (ADH) oxidizes alcohol into acetaldehyde (AA), which is a known
carcinogen. Aldehyde dehydrogenase (ALDH) oxidizes AA into acetate. Therefore …

Plasma inflammatory cytokines and survival of pancreatic cancer patients

A Babic, N Schnure, NP Neupane… - Clinical and …, 2018 - journals.lww.com
Objectives: Inflammation and inflammatory conditions have been associated with pancreatic
cancer risk and progression in a number of clinical, epidemiological, and animal model …

Biochemical diagnostics of pancreatic cancer-Present and future

W Jelski, B Mroczko - Clinica Chimica Acta, 2019 - Elsevier
Pancreatic cancer is one of the deadliest cancers having an exceptionally high mortality
rate. Despite a relatively low incidence (10th among cancers), it is the fourth leading cause …

Identification of serum biomarker panels for the early detection of pancreatic cancer

J Song, LJ Sokoll, JJ Pasay, AL Rubin, H Li… - … Biomarkers & Prevention, 2019 - AACR
Background: Pancreatic cancer is a deadly disease for which available biomarkers, such as
CA19-9, lack the desired sensitivity and specificity for early detection. Additional biomarkers …

[HTML][HTML] GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated …

YL Li, JT Chang, LY Lee, KH Fan, YC Lu, YC Li… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Radiotherapy is an integral part for the treatment of head and neck cancer (HNC), while
radioresistance is a major cause leads to treatment failure. GDF15, a member of the TGF-β …

Growth differentiation factor 15 contributes to marrow adipocyte remodeling in response to the growth of leukemic cells

W Lu, Y Wan, Z Li, B Zhu, C Yin, H Liu, S Yang… - Journal of Experimental …, 2018 - Springer
Background The adipocyte remodeling, including of the morphological change, might
indicate special pathological function. Our previous study found that the morphological …