Background Identifying and removing reference duplicates when conducting systematic
reviews (SRs) remain a major, time-consuming issue for authors who manually check for …

Meta-analytic techniques have been widely used to synthesize data from animal models of
human diseases and conditions, but these analyses often face two statistical challenges due …

Background Researchers performing high-quality systematic reviews search across multiple
databases to identify relevant evidence. However, the same publication is often retrieved …

Systematic reviews and meta-analysis are the cornerstones of evidence-based decision
making and priority setting. However, traditional systematic reviews are time and labour …

Background Despite extensive investment, the development of effective treatments for
Alzheimer's disease (AD) has been largely unsuccessful. To improve translation, it is crucial …

Over the past two decades, databases and the tools to access them in a simple manner
have become increasingly available, allowing historical and modern-day topics to be …

Systematic reviews and meta-analyses have been increasingly recognized for their potential
value in pre-clinical research, but their applications have not been extensively explored in …

I would also like to thank my colleagues, friends, and family who have supported me along
the way. Firstly, I would like to thank my supervisor Dr Emily Sena. You are not only an …

Simple Summary The 3Rs principle indicates the measures to refine, reduce, and replace
the use of animals in research. Thirteen out of the twenty-seven European countries already …

Preprints provide an indispensable tool for rapid and open communication of early research
findings. Preprints can also be revised and improved based on scientific commentary …