Autoantibodies-enemies, and/or potential allies?

H Ma, C Murphy, CE Loscher… - Frontiers in Immunology, 2022 - frontiersin.org
Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …

Clinical implications of anti-idiotype antibodies in COVID-19

AK Shukla, S Misra - Journal of Basic and Clinical Physiology and …, 2022 - degruyter.com
Idiotype-based therapeutics have failed to deliver their promise, necessitating rethinking of
the concept and its potential to develop a viable immunotherapy method. The idiotype based …

Idiotope-driven T-cell/B-cell collaboration-based T-cell epitope prediction using B-cell receptor repertoire sequences in infectious diseases

Y Nakamura, ML Moi, T Shiina, T Shin-I, R Suzuki - Viruses, 2023 - mdpi.com
T-cell recognition of antigen epitopes is a crucial step for the induction of adaptive immune
responses, and the identification of such T-cell epitopes is, therefore, important for …

Immune Jumping in Autoimmune Long-Covid

H Kohler - Monoclonal Antibodies in Immunodiagnosis and …, 2024 - liebertpub.com
This Long-Covid disease, mild or severe, is multiorgan or system-wide, spanning from
fatigue to clotting abnormalities and autoantibody. The spectrum of different symptoms in …

Jerne's “immune network theory”, of interacting anti‐idiotypic antibodies applied to immune responses during COVID‐19 infection and after COVID‐19 vaccination

S Kurbel - BioEssays, 2023 - Wiley Online Library
Abstract Niels Kaj Jerne has proposed the “immune network theory” of interactions among
anti‐idiotypic antibodies, able to interfere with humoral responses to certain antigens. After …

Проблемы и коллизии вакцинологии

ЕП Харченко - Эпидемиология и Вакцинопрофилактика, 2024 - epidemvac.ru
Аннотация В статье рассматриваются ограниченность защитного потенциала
иммунной системы, определяемая особенностями эволюционных механизмов …

What Can We Learn from Research with Monoclonal Antibody 1F7?

H Kohler - Monoclonal Antibodies in Immunodiagnosis and …, 2022 - liebertpub.com
1F7 is a monoclonal antibody that recognizes an idiotypic determinant expressed on primate
antibodies binding to HIV-1 and hepatitis C proteins. This monoclonal antibody was used as …