We review the mechanisms responsible for amino acid homeostasis in Saccharomyces
cerevisiae and other fungi. Amino acid homeostasis is essential for cell growth and survival …

Neutron protein crystallography is a powerful tool for investigating protein chemistry
because it directly locates hydrogen atom positions in a protein structure. The visibility of …

Thin protein films of gelatin molecules grown on flexible substrates have been utilized to
fabricate moisture-induced energy-harvesting devices, which work as self-biased sensors …

The bacterial melibiose permease (MelB) belongs to the glycoside–pentoside–hexuronide:
cation symporter family, a part of the major facilitator superfamily (MFS). Structural …

Neutron scattering studies provide important information in structural biology that is not
accessible using other approaches. The uniqueness of the technique, and its …

Carbonic anhydrases (CAs) catalyze the hydration of CO2 forming HCO3–and a proton, an
important reaction for many physiological processes including respiration, fluid secretion …

The scattering of neutrons can be used to provide information on the structure and dynamics
of biological systems on multiple length and time scales. Pursuant to a National Science …

Dihydrofolate reductase (DHFR) catalyzes the NADPH-dependent reduction of dihydrofolate
(DHF) to tetrahydrofolate (THF). An important step in the mechanism involves proton …

Secondary active transporters are fundamental to a myriad of biological processes. They
use the electrochemical gradient of one solute to drive transport of another solute against its …

Neutron crystallography was used to directly locate two protons before and after a pH‐
induced two‐proton transfer between catalytic aspartic acid residues and the hydroxy group …