Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor
neurons, which results in weakness and atrophy of voluntary skeletal muscles. Treatments …

Enhancing neurogenesis within the hippocampal dentate gyrus (DG) is critical for
maintaining brain development and function in many neurological diseases. However, the …

MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …

Microtubule proteins form a dynamic component of the cytoskeleton, and play key roles in
cellular processes, such as vesicular transport, cell motility and mitosis. Expression of …

Background Cancer is one of the most dreaded diseases characterized by uncontrolled
proliferation of abnormal cells that occurs due to impairment of cell division and apoptosis …

Abstract miR-124 and miR-506 are reportedly down-regulated and associated with tumor
progression in many cancers, but little is known about their intrinsic regulatory mechanisms …

Mesenchymal stem cells (MSCs), distributed in many tissues in the human body, are
multipotent cells capable of differentiating in specific directions. It is usually considered that …

Background Breast cancer (BC) is the most common cancer among women and it is
responsible for more than 40,000 deaths in the United States and more than 500,000 deaths …

The ventricular-subventricular zone harbors neural stem cells (NSCs) that can differentiate
into neurons, astrocytes, and oligodendrocytes. This process requires loss of stem cell …