The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

One effective solution in the analysis of complex mixtures, including protein or cell
hydrolysates, is based on chemoselective derivatization of a selected group of compounds …

Chemical derivatization is a very promising technique for improving analysis of peptides by
mass spectrometry (MS). Thereinto, development of novel tags compatible with MS and/or …

Matrix-assisted laser desorption ionisation (MALDI) mass spectrometry allows for the rapid
profiling of different biomolecular species from both biofluids and tissues. Whilst originally …

Mass spectrometry is a sensitive and specific method of proteome analysis. Various
strategies are applied to increase the ionization efficiency of peptides and determine or …

In this study, a novel type of pyridinium-based tags, 1-[3-[(2-iodo-1-oxoethyl) amino] propyl]-
4-methylpyridinium bromide (IMP) and 1-[3-[(2-iodo-1-oxoethyl) amino] propyl]-4 …

Tuberculosis, caused by Mycobacterium tuberculosis, is one of the world's deadliest
communicable diseases and present in all regions of the world. The Global Tuberculosis …

Масс-спектрометрия (МС) в настоящее время служит мощным методом анализа и
исследования веществ. Развитие методологии, инструментальной базы и способов …